consciousrepo
₿enjamin

https://www.consciousrepository.com/

Biotech in Saint Louis. Complex systems.

Public Key

npub16sq23d0f0algnztk65gmsa9fj6p90anap2reucwlk94zxge7ve3s5pscjz

NIP-05 Address

Profile Code

nprofile1qqsdgq9gkh5h7l5f39md2ydcwj5edqjh7e7s4pu7v80mz63ryvlxvccpz3mhxue69uhhyetvv9ujuerpd46hxtnfduq3qamnwvaz7tmwdaehgu3wwa5kuegpzemhxw309a6k6cnjv4kzumr0vdskcw358q6rsqg4waehxw309ajkgetw9ehx7um5wghxcctwvsq3gamnwvaz7tmwdaehgu3wdau8gu3wv3jhvqghwaehxw309ahx7um5wghxvmt59emkj73wvf5h5dn5uaz

Publishing to

Author Public Key

npub16sq23d0f0algnztk65gmsa9fj6p90anap2reucwlk94zxge7ve3s5pscjz

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Last Notes

2026-04-22 03:41:40 UTC

the difference in price between a token and the time it saves you is the arbitrage opportunity

2026-03-28 15:52:30 UTC

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have you ever read jw dunne’s ‘an experiment with time?’

2026-03-17 18:43:01 UTC

> our greatest moat?
> **chuckles**
> **pulls left hand out of pocket and grabs tip of hat to pull it down just a little lower**
> oh investor, our greatest moat is that it would take our most competent competitors WEEKS to order the same materials we have from japan.
https://blossom.primal.net/bf94790f81fa86685bd34248c10f35a528fc09e7ef136afc997be08fd82601a9.jpg

2026-03-11 04:46:25 UTC

enterprise ai plans: incognito mode that charges you for pretending not to listen

2026-03-11 04:46:11 UTC

gating a working product behind a sales demo is telling your best customers to go use your competitor's free trial

2026-02-15 17:12:04 UTC

cubans waiting to withdraw the maximum ~$6 usd from the bank because they don’t have faith in their government. pensioners sleep in the street sometimes to save their spot for the next day to make sure they can collect before they are dry.
https://blossom.primal.net/f49fb2919f2054b7225853943ac688b0a6518aad2aac233260ebbbe93ad331e6.jpg
https://blossom.primal.net/b4bada7e39186579d2ea7bb9a677ae03998b1f136d4e3416dc628c388d3b5e8f.jpg

2026-02-10 21:03:44 UTC

communist govt produces capitalism in its lowest class and capitalist govt produces communist in its lowest class
https://blossom.primal.net/7c32f847e28d8e68fa08b4d454c97c5d187d5e0d2d24f4e8b87844cf8894c3ba.jpg

2026-02-03 04:55:21 UTC

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not at all once the plan was in place
https://blossom.primal.net/10a9f58185eeb187f9eab585b9f735a60016a655b622e3275c9855704cc46b3a.mov

2026-02-03 04:45:35 UTC

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thats my boy, go get ‘em 📈

2026-01-30 20:43:41 UTC

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Uh oh- alfred pls dont tell him

2026-01-18 16:13:56 UTC

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@npub1src…trts

2026-01-16 06:56:19 UTC

universities should operate like staffing agencies- if they can’t place you in a job that justifies the degree’s price tag, you collect UBI from the endowment until they do.

2026-01-14 22:57:26 UTC

ashton kutcher is hiding nearby, i know it
https://blossom.primal.net/db4583c3adbb937c0af8454b8846c330aeef0c0efaf31d364c597a57d74a8f57.jpg

2026-01-04 19:40:46 UTC

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just finished anne carson’s ‘eros the bittersweet’
glukupikron is a fun word, more closely translated to sweet bitter than the modern analog.
tl;dr- desire requires three components: the lover, the beloved, and the gap between them.
the moment you possess what you want, eros dissolves.
the reaching is the thing.
#nevent1q…w0w6

2026-01-04 19:31:14 UTC

https://blossom.primal.net/98ea780e9c24f0c1a457127ddea212326df28004110c5c1996cac43d96161264.jpg

2025-12-23 20:02:37 UTC

let the holiday reading begin
https://blossom.primal.net/09843a7561cc34081e8e15fbbb540b440060bcd898d07f26860986c0649ce918.jpg

2025-12-21 20:11:36 UTC

The Iliad is a poem about conflict between the hierarchy of status and the hierarchy of merit.

2025-12-21 17:43:05 UTC

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house

2025-12-21 17:42:43 UTC

Heinz Bienefeld’s Babanek Hous
https://blossom.primal.net/0e30775324bc9b928483b6a77e00421d3def9ab8524a797903b0be82b9025c1d.jpg
https://blossom.primal.net/c60be42baa7a285b9927d7ca3838df4a1fa57c2df01c6d4ba4c19badbd2c470d.jpg
https://blossom.primal.net/4f182be5a267316fd66166caf3bc3e9d49f2e005104668f09124ee5dce582d1e.jpg
https://blossom.primal.net/9c09a60e492f838024af62e7d5084dbcae9ec4d79b5a9a459aa154800bf5347a.jpg

2025-12-21 17:40:16 UTC

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a meditation written after a recent pilgrimage
#naddr1qq…04ma

2025-12-09 03:12:37 UTC

idk should we just leave the back open, view is pretty gr8
https://blossom.primal.net/6343b77095e43a9ef49ef84243a59a8e16474deb42d84ecec5d62ca464c9ce67.jpg

2025-12-02 06:25:48 UTC

lots of steganography in the desert because we are all looking for an oasis
there is a nice meditation point at the top of Anderson Overlook outside Los Alamos.
Petroglyphs from the heroes of the manhattan project, or even earlier relics from the ranch school boys that preceded them
https://blossom.primal.net/e20a819dd7e4beb0c764dbdc1264935c4776f3d20ea0bcf2e0d3564c234a88f6.jpg

2025-11-27 15:56:01 UTC

defending our attention is defending our capacity for self-determination. if we can’t focus, we can’t think clearly, and if we can’t think clearly, we can’t govern ourselves or pursue meaningful goals.

2025-11-25 16:39:23 UTC

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2025-11-25 16:38:06 UTC

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@npub1v5p…ejml

2025-11-23 19:01:19 UTC

a miracle is an ingression of a higher level agency. maybe on occasion to persuade. such a synchronicity makes it impossible to look away and implies you should move in that direction
https://thoughtforms.life/a-conversation-with-fr-robert-marsland-and-pavel-chvykov/

2025-11-22 20:47:57 UTC

what do you think is it salvageable?
https://blossom.primal.net/a9e877ceda1b54c8124d87b25025f13a817734d0a43691454a1b76713f526403.jpg

2025-11-22 02:23:08 UTC

from visualize value // jack butcher
https://blossom.primal.net/2805c547468595f93b8f4412524afbaac75231e986a163810217ce0acab2d8a1.jpg

2025-11-21 18:08:43 UTC

This morning I tried to move money from one account I own to another in order to have enough funds to clear a check I'd just written.
First problem: a limit on how much I could move at one time. Ok, call the bank, increase the limit. Check.
Problem number two: I move the funds and the transaction is pending. Well, I need this check to clear now, so let me call the banks because I can't wait until Monday for this. One bank says their ACH is sent and with the Fed. The other says the ACH is with the Fed and not going to clear until they release it.
What is the Fed doing with my money right now, and why is it going to take them 2-3 business days to release it from one bank to another via ACH?
Imagine every single ACH transaction that this is happening with right now. Then imagine the interest that the Fed collects just by bottlenecking that transfer for 2-3 days on each of those transactions.
If we'd been sending value over Bitcoin, it would have cleared in 10 minutes with no intermediaries with broken incentives in between.
Every time I need to deal with money in the fiat system, I am reminded that the money I have in that system is not mine, and that I am participating in a game of Monopoly. The bank could run out of its fake bills any time, and the only thing it can do then is make more.
Every time they do this, it steals buying power from every hard-working individual who saves money earned for their work in USD.
In his most famous book written in 1970, Albert Hirschman proposes that when dealing within a broken system, you have three options: use your voice and speak up, be loyal and trust in the system, or exit.
In the case of the monetary system of the United States, I have no voice. I have no reason to be loyal, and so I choose to exit.
That is why I buy Bitcoin. Every. Single. Day.

2025-11-16 16:46:16 UTC

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this is a good podcast with the author and interviewer @nprofile…s6sy
https://fountain.fm/episode/NwzeryDe5llTauNUf9fK

2025-11-14 05:29:58 UTC

Back to back I bounce from things that feel like they are the start of momentum and I get distracted, but by what? Something else that I should be doing, now. Something else that I need to do, tomorrow. Something I did wrong, yesterday.

2025-11-13 17:51:05 UTC

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https://blossom.primal.net/c4be017c657b2b43147fa1c1628acc34ea1ca6fa284e1bdeef94399b4c7bfcd4.mov
#nevent1q…sjxf

2025-11-12 22:38:20 UTC

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the prospect of a populist revolution seems far more likely coming from the right because the left lacks charismatic leadership and organization.
your Fuentes post the other day was poignant

2025-11-12 15:33:39 UTC

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rebuilding it
https://blossom.primal.net/b57e1659930c85c3a81896d32a753934a0d2552936a98d27476159cd173441ca.mov
#nevent1q…tpag

2025-11-11 22:53:38 UTC

a brain <> ai interface piloted from our lab in saint louis
https://patrickseebold.substack.com/p/i-connected-my-brain-to-chatgpt

2025-11-06 05:48:21 UTC

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looking for a job in what space/skillset

2025-11-05 02:03:07 UTC

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ah- linux distro.
Omarchy

2025-11-05 01:53:29 UTC

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not sure yet- and it has the same trackpad as a MacBook which is an @nprofile…lkvk selling point

2025-11-05 01:45:10 UTC

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under consideration but have you seen
https://us.starlabs.systems/products/starfighter?variant=55247122432380#info
Willing to give up some sovereignty for feel good rectangle

2025-11-04 15:52:11 UTC

bitcoin 🤝 farmers
https://www.agweb.com/news/business/bitcoin-set-revolutionize-us-agriculture

2025-11-04 05:40:02 UTC

decided on the linux distribution now need to pick a laptop

2025-11-04 05:39:07 UTC

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dont want to seem difficult but can you like give one real example of this

2025-11-04 05:38:09 UTC

the mandela effect is an antimeme deployed by the marketing agency union

2025-11-03 04:36:26 UTC

an East of Eden movie directed by paul thomas anderson would be a magnum opus

2025-11-02 17:57:24 UTC

the only questions that matter from a risk perspective are:
1) how much can i outcompete interest in value per unit time and
2) how much more expensive is inflation going to make what i want over the time period i am acting in?
subtract answer 2 from 1 to adjust risk assessment accordingly

2025-11-01 06:13:46 UTC

happy Halloween
https://blossom.primal.net/af817aac8f7fa65b824eb69429713974b2be9277c5e68e06862f3d8620535f7b.jpg

2025-10-31 21:35:42 UTC

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ah yes, the southwest Missouri special

2025-10-31 18:13:04 UTC

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laptop and meeting class*

2025-10-31 18:12:29 UTC

non profits used to be a vehicle for accepting money so that people with money and no time who want good done and people who want to see more of this good in the world can immediately support each other but then they get so big that people start paying themselves a salary to be full time raising money to do more good and then it all gets bloated and grifty as more people are getting by as the laptop and meeting glass and less people are spending time building community gardens

2025-10-30 03:37:52 UTC

iykyk
https://blossom.primal.net/7c745c8d765ef621e146794d103c01f1866801362b2cb4f72aca4d8c57a05412.jpg

2025-10-22 21:59:37 UTC

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not yet

2025-10-21 04:01:16 UTC

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literally just this and a chicken light
https://www.amazon.com/Woods-Clamp-Aluminum-Reflector-Listed/dp/B000HHQ94C/ref=sr_1_7?dib=eyJ2IjoiMSJ9.TLszqCgnoI8njrauxdbuAxFRZ8P3EGST5Y-Me4S1xGBG5Ozzxp6XVDuPSN9upgCDmB1-oAPPbS_iSRRvclRCrjJ74I0XRm_0Lhrt6ELqVmodvHVeeWeNABgbHM-EFH-uEdOpMCBavBwANgJZFLhC3JJLelf7neTmzZ47U6IvhqBgUIGBh6ml__sRJV1CKaB1fd-46JF-3TYVvMLU3u_HJA8YIsPcBdNu3KZGuy8oUuPCIGSpRbD2faAZ8MzwojhBMHgbKY1VpMeKrjcIuU1uOGZJnwQMRA1prfV4-DuyQAo.EYLJ4WbypZIZAPPvB_A6ZPk-Zxea-vikhdQGWZV_A9Q&dib_tag=se&keywords=chicken+light&qid=1761019248&sr=8-7

2025-10-20 21:50:04 UTC

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also the tornado was literally over 5 months ago
https://blossom.primal.net/c65bce59ff70b10cf5182b41bb8909c8cfde693bdfb0782ff1d8c4090ab99f8f.jpg

2025-10-20 21:49:20 UTC

got hit by a tornado and the government called asking what they could do to help so I said NO
https://blossom.primal.net/3ef63243b3b605cd60ec96d0872e89a2cf7e0aa000355cb6a36ab7b00ec00833.jpg

2025-10-20 19:34:36 UTC

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ask me in a week, first day, about 6 hours in and so far so great

2025-10-20 18:47:08 UTC

red light maxxing at the office
#peatstr
https://blossom.primal.net/f22bd4fffbdd7b37c95fd60675d36711151d65d0b8e621b1d9c137a659c9e71d.jpg

2025-10-19 15:58:34 UTC

gm
https://blossom.primal.net/11f4adfda384c65185b71045a383e68fa76f38092002c0c1da385c80855d9f18.jpg

2025-10-18 23:28:32 UTC

then and now
https://blossom.primal.net/838b4b3fe416de6d026c185c553c4d68c719c5b83a19d36aaacb603ec1c13883.jpg
https://blossom.primal.net/aaf0df6cb8b43559626749b9e0e03a5192a3eea4464127bad8a294c327b64612.jpg

2025-10-16 18:14:49 UTC

is this a dream? am i awake rn?
https://blossom.primal.net/4eb5089a1b3467507a3bc264498bfb21091089f526defe16d16532e800c168a7.mov

2025-10-16 06:01:22 UTC

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hash rate up, block rewards go down, some miners sell off or consolidate, this is historically followed by a dip?

2025-10-16 05:39:29 UTC

Bitcoin going on sale soon? Normies ready to surf?
https://blossom.primal.net/1b26602ab54d4aebf6763a600fbb9c404314fe9a24b0afae771c7e2ff75ee9b8.jpg

2025-10-13 23:08:17 UTC

everytime i pay for steak n shake with bitcoin i buy another $100 worth on @nprofile…lqdu to celebrate the inevitable
https://blossom.primal.net/032415edbada2179f37b1a2aed67d17f8e323589c00498eaae83c4fd07bb050d.jpg

2025-10-08 19:29:44 UTC

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yoooo, great follow here 👇
#nevent1q…8lmm

2025-10-08 18:48:46 UTC

I’ve carried a notebook on me at all times for 10 years. Knowing this- a close friend got me one of those ai pendents that life logs everything. Been using it for a few days now and despite initial skepticism- actually really like it. I get a daily transcript of everything with an option to keep audio. All the major LLMs are integrated so am then able to ask questions using this data as context, eg: What book did Stephen recommend over lunch? What was the name of the software David mentioned?
It also automatically generates a list of To Dos from the day’s log which has been surprisingly helpful.
This specific one(Limitless) also has an open api with model context protocols so you can build custom workflows off of transcripts. Going to spend some time trying things with this.
Data security is a huge question. I have been cognizant to let people know I am wearing it during some meetings and this doesn’t seem to affect transparency of conversations however I notice I am self reflecting more which is a down side. All in all not sure if this pattern will stick but going to keep playing with it.
https://blossom.primal.net/fa11c4485373cda5cfa5a8e0d08db365c91352a029f678c84560828cbe9b4320.jpg

2025-10-06 00:13:32 UTC

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hey- just tried to zap you and looks like there is an error?
https://blossom.primal.net/c0d26357c4ebb1ba8e6d2420289e0c75d32f9ddf7f10390e4ef9fad0750d1ca5.png

2025-10-03 21:36:01 UTC

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our work has focused on the patterns associated w/ reprogramming differentiated/aged cells to stem cells(proxy for 0 age phenotype) and aiming now to mimick the 0 age phenotype patterns. there is scattered literature on the age related changes across cell types.
here's a recent one from levin focusing on senescing keratinocytes
https://www.sciencedirect.com/science/article/pii/S2589004225015366

2025-10-03 20:55:05 UTC

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basically- yes. early work we did was with electromagnetic fields but because these frequency ranges wont translate to stimulating deep tissue because of surface attenuation, we are now mainly using static magnetic fields and ultrasound for power + depth penetration

2025-10-03 14:28:24 UTC

today i learned there is a gigachad out there building open source farm equipment https://opensourceecology.dozuki.com/
https://blossom.primal.net/74eccec56a66835fafe5edace570a4252f9664b4e948e3d2ce1258090226487f.png

2025-10-03 14:14:33 UTC

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10/ Why solve subsystem delivery and timing nightmares when it may be possible to use external spatial control?
This is why we went all in on fields.
https://primal.net/e/naddr1qvzqqqr4gupzp4qq4z67jlm73xyhd4g3hp62n95z2lm86z58nesalvt2yv3nuenrqqdk6mmvv43h2mr9wvkhwmmwwskkgetxv4shgttpva5kuecsqn80k

2025-10-03 14:13:50 UTC

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9/ The best in vivo study was on transgenic mice with doxycycline-inducible OSKM. Systemic short cycles rejuvenate fast tissues (pancreas, muscle) while avoiding teratomas.
This requires genome editing for the switch which is not feasible for adults now. Even with universal insertion, tissue reprogramming speeds vary (liver > kidney > skin > neurons), which means current approaches need custom circuits for each cell type.

2025-10-03 14:13:39 UTC

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8/ Since 2006, biologists been able to reprogram any cell type to stem cells. The logical extension is scale this tech to rejuvenate organs or humans.
Top longevity firms (Altos, Calico, Retro, New Limit) raised billions on this assumption however their molecular methods limit spatial/temporal control.

2025-10-03 14:13:25 UTC

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7/ We know organ replacements work individually, and multiple companies are now exploring knocking out the forebrain in human clones to grow mature bodies for organ harvesting or using the whole thing as a replacement vehicle.
We’re not pursuing this direction both because other players have this space covered and the approach has bad aesthetics. https://blossom.primal.net/2efd38d0e1c1a8e35433972be7c54b1bc6b8d1310a10756cdc7b6df48e1e08f5.jpg

2025-10-03 14:12:41 UTC

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6/ Re: 1, the effort to develop ways to address the full set of damage from aging would require so many concurrent interventions that it's smarter to focus on upstream causes instead.
Plus, the pharmaceutical landscape has this covered. The race in drug discovery to target specific indications will produce drugs for the net set of aging byproducts.

2025-10-03 14:12:28 UTC

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5/ There are essentially three approaches to tackling the contributors to aging.
- Removing accumulated damage.
- Replacing organs or the whole body.
- Reprogramming aged tissue to a more youthful phenotype.
We've hung our hat on approach 3 for a few reasons.

2025-10-03 14:12:16 UTC

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4/ At $500,000 per compound for replicated mouse longevity assays benchmarked from NIA Interventions Testing Program protocols (200-300 mice over 3 years), that totals $93.5 quadrillion.
Oh, and add a $1 billion for the lone projected success case to validate in humans.

2025-10-03 14:12:03 UTC

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3/ For maximum lifespan across, the mean hits 2.56%, median 1%, standard deviation 5.26%. Rats show similar modesty with 23 entries averaging 4-5% extensions.
Fitting a normal distribution to the average median changes yields a 5.34e-12 probability of >=50% extension, meaning 187 billion molecules screened to expect one hit.

2025-10-03 14:11:49 UTC

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2/ Assume there is a single drug that could lead to a 50%+ lifespan extension outcome.
We can infer the probability of this existing by looking at the DrugAge database- a single source that aggregates data from thousands of lifespan studies across species.
Mice are the organism most closely related to humans with 100+ reproduced studies in the database.

2025-10-03 14:11:24 UTC

🧵 A molecule is not going to solve aging.
1/ Our work has led us to dropping drugs and gene therapies entirely.
To most pursuing traditional routes, this sounds radical. To us, it is common sense. https://blossom.primal.net/54e9dff92976b5d3975d0daaf047cf4cca439196ffaafc13cfc039228346addd.jpg

2025-10-01 02:07:03 UTC

rewatching The Big Short to celebrate the govt shutdown tomorrow and damn is this movie a masterpiece

2025-09-29 16:14:20 UTC

Thought patterns are more fundamental than reality. Reality becomes organized in such a way for a thought pattern to be able to interact with other thought patterns.

2025-09-28 19:38:22 UTC

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increases basal metabolic rate. i prefer maple syrup to honey in my coffee personally and oj intake is only limited by supply

2025-09-27 22:03:26 UTC

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has dramatically improved my energy levels from 3-6pm

2025-09-27 22:02:55 UTC

‘solipsism is useful when interpreting dreams or art’

2025-09-27 20:29:36 UTC

pain happens when synchronization is disrupted

2025-09-27 20:27:48 UTC

https://open.substack.com/pub/punkrockyoga/p/embodied-cognition

2025-09-24 20:58:56 UTC

first tickle sesh happening now
https://blossom.primal.net/afcc47bad1624104ade703b89d01216f4bb54591b601ca790f4c4d36082f1aac.jpg

2025-09-22 16:46:06 UTC

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it is fun to see real things. this guy is going to tickle alot of cells
https://blossom.primal.net/7b8401d78b204f623f3a4caf87a019c1cffbd5f3a7b2e8b36a0b606ab18de07c.jpg
#nevent1q…2s3m

2025-09-22 16:30:01 UTC

a friend of the lab is using our transcranial magnetic stimulation device to run some experiments in the lab this week. filming for fun
https://blossom.primal.net/4769c38e0fa0aa7ba0aa915bed68d81b97cc55f08a6bfed6fdcadfeb5c488d9b.jpg

2025-09-19 17:57:20 UTC

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more simple question:
is cell identity and aging inherently linked
#nevent1q…ecs2

2025-09-19 17:50:20 UTC

tldr epigenetic measured aging increases when critically ill- not much out there for this but curious degree to which epigenetic aging clocks accelerate and then reverts to norm when sick, might elucidate something
https://pmc.ncbi.nlm.nih.gov/articles/PMC10857665/

2025-09-19 16:58:58 UTC

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marry one

2025-09-17 04:09:17 UTC

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ha! that's funny- i havent read broken money yet but a copy is sitting on my shelf

2025-09-16 23:33:32 UTC

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This passage is actually from this book-
https://blossom.primal.net/ef4b4a2259c5119f54632ae263496ff8c3d32384881adad1bc0f4da58cb22802.jpg

2025-09-16 22:18:53 UTC

https://blossom.primal.net/fb842a60e9d150b7ad29bf586d8c36ba22828be4bbe2339edbf5a5bebdeb29e7.jpg

2025-09-16 19:09:47 UTC

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thank you for the share. we're both in the same neck of the woods- you're welcome by anytime. here 9-9 most days

2025-09-16 19:00:19 UTC

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its a little christian coded but alpha in here
https://blossom.primal.net/a1be90b797909421f351a9de0cde7f1e970916931e00f4a07289a574cbc8bea7.jpg

2025-09-16 18:49:35 UTC

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check out our white paper
https://www.aion.bio/aion.pdf

2025-09-16 18:48:45 UTC

I am hiring engineers to develop hardware at the intersection of acoustics, magnetism and RF. functional schizoids preferred
https://blossom.primal.net/e71e86ffbb6985f63e760a1e588b310e8bf0c1873dbdcd8a3803b1ab3efff248.jpg

2025-09-16 18:36:58 UTC

no opinion yet, just received but it is aesthetically pleasing
https://blossom.primal.net/d0dab1586d0c7210684e92a739a110c0eb83e449dac9e91def81fca84df30dab.jpg

2025-09-14 15:14:34 UTC

legend has it- these are the finest cigarettes in the world. cant confirm.
https://blossom.primal.net/1a39f103a15c363d63e8ea05d3301c56de6685a85f89e071c30e1da8bdc3f95c.jpg