Hilda Bastian

Scientist (PhD; she/her), writer, cartoonist. 🦘 I blog about metascience, science history, epidemiology, grief, social media data, & evidence generally. Following and reporting on next generation Covid vaccines. And I write at The Atlantic sometimes. Newsletter: Living With Evidence https://hildabastian.wordpress.com/

#MetaScience #SystematicReviews #Epidemiology #ClinicalTrials #Grief #Vaccines #Wikipedia #History #HistSci #Science #OpenScience #OpenSocialWeb

Living With Evidence (via Mastodon follow): Living With Evidence (npub1hc5…wv4r)
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Wikipedia: https://en.wikipedia.org/wiki/User:Hildabast

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Published at

2026-04-24T01:49:21Z

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Last Notes

2025-09-21 07:43:05 UTC

Want to be able to start micro-editing on Wikipedia in a few minutes – and know why you could be very glad you did? Then my new post @npub1cgw…rh79 is just what you need!
https://absolutelymaybe.plos.org/2025/09/21/wikipedia-is-vital-channeling-energy-into-micro-edits-is-a-win-win-win/
#Wikipedia

2025-08-28 09:03:08 UTC

With federal workers, equity, & government statistics under attack, my latest post @npub1cgw…rh79 is a tribute to a transformative First Nations statistician at the US Census Bureau, Edna Paisano (1948-2014):
https://absolutelymaybe.plos.org/2025/08/28/equity-in-first-nations-census-data-a-tribute-to-edna-paisano-1948-2014/ ...1/2
#WomenInSTEM #Statistics

2025-07-01 06:37:18 UTC

A big first for next generation Covid vax! A manufacturer is accelerating a "universal coronavirus vaccine." It's set to be the first pancoronavirus vax going into phase 2 trial – & a mucosal form might be developed, too.
More in my latest Covid vax update @npub1cgw…rh79
https://absolutelymaybe.plos.org/2025/06/30/a-universal-coronavirus-vaccine-pushing-forward-nextgen-covid-vax-update-30/
#Vaccines #Covid #Covid1

2025-06-27 06:42:53 UTC

I've been diving into the evidence on Covid vaccination in pregnancy, & sorting through misinformation – including the claim that Pfizer never reported on its pregnancy trial. And I ended up relieved!
Check out results of studies in more than 1.5 million vaccinated pregnant participants in my latest @npub1cgw…rh79 https://absolutelymaybe.plos.org/2025/06/27/digging-into-the-evidence-on-covid-vaccines-in-pregnancy/
#Vaccines #Covid #Covid19

2025-06-01 06:08:26 UTC

Lots to learn about nasal Covid vax in my latest nextgen vax update @npub1cgw…rh79:
- 1st trial results for intranasal Covid DNA vax, with some signs it can reduce infection;
- Researchers in Japan developed over 200 monoclonal antibodies from nasally-vaxed mice to study immunity's molecular processes;
- UK authorization for nextgen mRNA vax being sought soon;
- US takes bizarre funding turn;
- 7th pancoronavirus vax going into clinical trial & more
https://absolutelymaybe.plos.org/2025/05/31/intranasal-vaccine-trial-results-and-more-on-preventing-covid-infection-nextgen-vax-update-29/
#Vaccines #Covid #Covid19

2025-05-01 06:16:53 UTC

Lots of next generation Covid vaccine news this month:
- Some good news at last about US Project NextGen trial funding for mucosal vax
- Preclinical studies for several intranasal vaxes showing prevention of transmission
- First preclinical results for a key French intranasal vax
- More data on the safety of self-amplifying mRNA vax
Plus more now @npub1cgw…rh79
https://absolutelymaybe.plos.org/2025/04/30/more-progress-in-vaccines-to-reduce-covid-transmission-nextgen-vax-update-28/
#Covid #Covid19 #Vaccines

2025-02-07 05:40:39 UTC

Now more than ever is a great time to be reminded of the powerful work of Margaret Morgan Lawrence (1914-2019) & honor her extraordinary legacy.
Decades before "social determinants of health" was coined, she spoke of "nature, nurture and noxia"
🧵
https://en.wikipedia.org/wiki/Margaret_Morgan_Lawrence
#BlackHistoryMonth #WomenInSTEM
https://files.mastodon.online/media_attachments/files/113/960/995/598/849/824/original/c8d23ee04d13c108.jpeg

2025-02-01 06:08:52 UTC

Want some good news? Sure you do!
Check out my update on next generation Covid vaccines this month @npub1cgw…rh79
* Another intranasal Covid vax went into clinical trial in Europe - it's the 32nd mucosal vax in trials
* An oral Covid vax trial got the green light to start recruiting thousands across the US
* More preclinical research showing reduced transmission
* International funding for a pancoronavirus vax in Canada
https://absolutelymaybe.plos.org/2025/01/31/another-intranasal-covid-vaccine-trial-more-good-news-update-25/
#Vaccines #Covid #Covid19

2025-01-03 05:23:35 UTC

Some Good News, At Least, for the Start of the Year
Last year ended with some good news for Covid vaccination: The European Medicines Agency recommended authorization for its first next generation Covid vaccine. Authorization for 30 European countries should follow in January or February. And manufacturers plan to apply for approvals in the UK and US this year as well – and perhaps elsewhere, too. The vaccine is the self-amplifying mRNA vaccine developed by the US…
https://hildabastian.wordpress.com/2025/01/03/some-good-news-at-least-for-the-start-of-the-year/

2024-11-21 22:08:53 UTC

"Look at the world! See it aching! It’s got so many problems—I promise you, there’s one with your name on it."
Lovely piece from Adam Mastroianni on underrated ways to change the world:
https://www.experimental-history.com/p/underrated-ways-to-change-the-world

2024-11-13 07:37:26 UTC

- reply

... In 1924, she joined RIKEN, Japan's premier national science institution, in addition to her teaching post. This photo was taken at RIKEN that year: She was 40.
There, she determined the molecular structure of shikonin, that purple pigment, and then the structure of carthamin. Carthamin gives safflower its color. She earned her doctorate with that work in 1929. That was just the second time a woman was awarded a PhD in science in Japan... 4/6
https://www.riken.jp/en/about/history/figures/
https://www.chemistryviews.org/chika-kuroda-the-pioneering-female-chemist-in-japan/
https://files.mastodon.online/media_attachments/files/113/474/496/508/424/485/original/dfdebdc18faa3dd3.png
https://files.mastodon.online/media_attachments/files/113/474/497/699/168/125/original/2fb398da22dad878.png

2024-11-13 07:33:02 UTC

This is the graduating class of 1916, chemistry division, Tohoku Imperial University.
There, at the end of the 2nd row, is the first woman to achieve a bachelor of science in Japan.
Her name was 黒田チカ, Chika Kuroda (1884-1968) & she was the daughter of a samurai...1/6
#WomenInSTEM #tbt
https://files.mastodon.online/media_attachments/files/113/473/858/594/383/206/original/c5a61e04ea7d43af.png

2024-11-07 23:27:29 UTC

Kicked my Twitter account to the kerb. Very satisfying. Can recommend.
https://files.mastodon.online/media_attachments/files/113/444/119/798/429/164/original/b39c32d442590008.png

2024-11-05 06:00:36 UTC

Optimism and Participating in Research
It's springtime here in Australia, and my garden is projecting optimism. I sure am grateful for it. Between personal grief, and all there is to despair or be anxious about in the world, cheery things are so very welcome. As I'm typing, the final day of voting is underway in the US election. I wrote last time that I decided not to place weight on the polling.
https://hildabastian.wordpress.com/2024/11/05/optimism-and-participating-in-research/

2024-09-01 06:18:40 UTC

Mucosal ("sterilizing") Covid vaccine trials are kicking into high gear.
Tens of thousands of next generation trial volunteers will be needed in the US soon. And we've got the first details for a Project NextGen "mini-efficacy" trial...
The first step for human challenge trials of intranasal etc vaxes is underway in the UK...
All this & more in my latest nextgen vax update @npub1cgw…rh79 ...1/2
https://absolutelymaybe.plos.org/2024/08/31/mucosal-covid-vax-trials-kicking-into-high-gear-update-20/
#Vaccines #Covid #Covid19

2024-08-29 09:24:42 UTC

This is Shyamala Gopalan Harris, Kamala Harris' scientist mother. 🥥
When her daughters spoke glowingly of her influence on them at the DNC, I was one of the 300,000 people who flocked to her Wikipedia page to find out more.
It left me curious about her life as a scientist & sent me down a rabbit hole. My new @npub1cgw…rh79 post is what I learned:
https://absolutelymaybe.plos.org/2024/08/29/some-context-of-what-came-before-shyamala-gopalan-harris-scientist-life/
#WomenInSTEM #tbt
https://files.mastodon.online/media_attachments/files/113/044/562/266/318/548/original/ce2711065bd66e3f.png