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2026-10-25 07:18:15 UTC

ctDNA clearance and outcomes for resectable lung cancer from NeoCOAST-2
Nature, Published online: 25 October 2026; [doi:10.1038/s41586-026-11328-3][1]
ctDNA clearance and outcomes for resectable lung cancer from NeoCOAST-2
[1]: https://www.nature.com/articles/s41586-026-11328-3
https://www.nature.com/articles/s41586-026-11328-3

2026-10-23 16:14:43 UTC

Author Correction: DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells
Nature, Published online: 23 October 2026; [doi:10.1038/s41586-026-11303-y][1]
Author Correction: DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells
[1]: https://www.nature.com/articles/s41586-026-11303-y
https://www.nature.com/articles/s41586-026-11303-y

2026-10-22 15:59:13 UTC

Current-Driven Molecular Machine with Rotation-Enhanced Conductance
Nature, Published online: 22 October 2026; [doi:10.1038/s41586-026-11312-x][1]
Current-Driven Molecular Machine with Rotation-Enhanced Conductance
[1]: https://www.nature.com/articles/s41586-026-11312-x
https://www.nature.com/articles/s41586-026-11312-x

2026-10-22 15:59:08 UTC

Can a 'lullaby' save coral reefs from extinction?
Nature, Published online: 22 October 2026; [doi:10.1038/d41586-026-03414-3][1]
From underwater speakers to growing super-corals, scientists battle to save reefs around the world.
[1]: https://www.nature.com/articles/d41586-026-03414-3
https://www.nature.com/articles/d41586-026-03414-3

2026-10-21 15:32:28 UTC

The anatomy of a personal health agent
Nature, Published online: 21 October 2026; [doi:10.1038/s41586-026-11161-8][1]
A multi-agent framework that coordinates data science, medical reasoning and health coaching over longitudinal wearable and clinical data to provide holistic personal health support is described.
[1]: https://www.nature.com/articles/s41586-026-11161-8
https://www.nature.com/articles/s41586-026-11161-8

2026-10-21 15:32:18 UTC

Additive manufacturing of ultralong and architected single crystals
Nature, Published online: 21 October 2026; [doi:10.1038/s41586-026-11185-0][1]
A free-form additive manufacturing method that uses alternating and pulsed heat inputs is described for fabricating metre-tall, centimetre-diameter single crystals of Ti-6Al-4V, as well as hard-to-process refractory metals, including W, Mo, Nb and MoNb alloys.
[1]: https://www.nature.com/articles/s41586-026-11185-0
https://www.nature.com/articles/s41586-026-11185-0

2026-10-21 15:32:03 UTC

Functional architecture of the human insula
Nature, Published online: 21 October 2026; [doi:10.1038/s41586-026-11175-2][1]
A functional architecture of the human insula links cytoarchitecture to directed and asymmetric electrophysiological interactions, with mechanistic implications for cognitive modulation of pain and interoceptive experience.
[1]: https://www.nature.com/articles/s41586-026-11175-2
https://www.nature.com/articles/s41586-026-11175-2

2026-10-21 15:31:42 UTC

Programmable design of functional proteins from natural language
Nature, Published online: 21 October 2026; [doi:10.1038/s41586-026-11205-z][1]
Pinal, a 16-billion-parameter artificial intelligence model, designs functional proteins from natural-language descriptions, demonstrating experimentally validated activities and improved CO2-fixation product yields without iterative optimization.
[1]: https://www.nature.com/articles/s41586-026-11205-z
https://www.nature.com/articles/s41586-026-11205-z

2026-10-21 15:31:35 UTC

GRP75-dependent SIMPA mediates inter-organellar quality control
Nature, Published online: 21 October 2026; [doi:10.1038/s41586-026-10733-y][1]
Proteotoxic stress drives formation of GRP75-dependent protein aggregates that signal through mitochondria–ER contact sites to activate targeted quality-control pathways, enabling selective clearance of damaged proteins and preserving mitochondrial integrity.
[1]: https://www.nature.com/articles/s41586-026-10733-y
https://www.nature.com/articles/s41586-026-10733-y

2026-10-21 15:31:25 UTC

Persistent neuronal stress signalling underlies Angelman syndrome phenotypes
Nature, Published online: 21 October 2026; [doi:10.1038/s41586-026-11165-4][1]
Genetic and proteomic analyses in human neurons and mouse models of Angelman syndrome (AS) show that loss of the ubiquitin ligase UBE3A leads to an overabundance of asparagine synthetase, and that this is linked with many AS phenotypes.
[1]: https://www.nature.com/articles/s41586-026-11165-4
https://www.nature.com/articles/s41586-026-11165-4

2026-06-29 16:10:34 UTC

Audio long read: Is the peptide craze backed by science? The promise behind the hype
Nature, Published online: 29 June 2026; [doi:10.1038/d41586-026-02063-w][1]
The market for unregulated peptides is huge. Has the hottest trend in wellness got ahead of the science?
[1]: https://www.nature.com/articles/d41586-026-02063-w
https://www.nature.com/articles/d41586-026-02063-w

2026-06-29 16:10:29 UTC

Family of magnetic field-boosted superconductors in rhombohedral graphene
Nature, Published online: 29 June 2026; [doi:10.1038/s41586-026-10815-x][1]
Family of magnetic field-boosted superconductors in rhombohedral graphene
[1]: https://www.nature.com/articles/s41586-026-10815-x
https://www.nature.com/articles/s41586-026-10815-x

2026-06-29 10:23:40 UTC

What’s the human cost of US research turmoil? A new film finds out
Nature, Published online: 29 June 2026; [doi:10.1038/d41586-026-01979-7][1]
Science is a complex, interconnected, deeply human enterprise involving hard grind — and funding cuts and grant delays have come as a sucker punch to many.
[1]: https://www.nature.com/articles/d41586-026-01979-7
https://www.nature.com/articles/d41586-026-01979-7

2026-06-29 10:23:35 UTC

How AI can crack open the ‘hidden curriculum’ for neurodivergent students
Nature, Published online: 29 June 2026; [doi:10.1038/d41586-026-01672-9][1]
Marisa Chrysochoou and Keivan Stassun argue that AI tools could help students to navigate academia’s unwritten rules.
[1]: https://www.nature.com/articles/d41586-026-01672-9
https://www.nature.com/articles/d41586-026-01672-9

2026-06-19 01:42:29 UTC

Stem cells banish severe autoimmune disease for 15 years
Nature, Published online: 19 June 2026; [doi:10.1038/d41586-026-01925-7][1]
Two people were the first to receive the therapy for a condition that damages the spinal cord and optic nerve.
[1]: https://www.nature.com/articles/d41586-026-01925-7
https://www.nature.com/articles/d41586-026-01925-7

2026-06-15 11:18:40 UTC

In the field — and sometimes in the lab — the simplest tool is best
Nature, Published online: 15 June 2026; [doi:10.1038/d41586-026-01885-y][1]
Technology has led to unprecedented innovation, but common household items can help make research more reproducible — and accessible.
[1]: https://www.nature.com/articles/d41586-026-01885-y
https://www.nature.com/articles/d41586-026-01885-y

2026-06-15 11:18:35 UTC

Why people should work together to shape the economy
Nature, Published online: 15 June 2026; [doi:10.1038/d41586-026-01889-8][1]
An economist sets out how communities can direct economic decisions and not just endure their consequences.
[1]: https://www.nature.com/articles/d41586-026-01889-8
https://www.nature.com/articles/d41586-026-01889-8

2026-06-03 09:30:16 UTC

Can an army of babies and dogs rescue psychology from its reproducibility crisis?
Nature, Published online: 03 June 2026; [doi:10.1038/d41586-026-01727-x][1]
Labs are teaming up to run a host of huge projects that aim to bring rigour to cognitive science.
[1]: https://www.nature.com/articles/d41586-026-01727-x
https://www.nature.com/articles/d41586-026-01727-x

2026-04-02 11:38:06 UTC

The Moon belongs to all of us — not just countries that can afford to reach it
Nature, Published online: 02 April 2026; [doi:10.1038/d41586-026-01051-4][1]
As humanity blasts off into a new space race, we need a model of exploration that emphasizes stewardship of other worlds, not exploitation.
[1]: https://www.nature.com/articles/d41586-026-01051-4
https://www.nature.com/articles/d41586-026-01051-4

2026-04-02 10:38:09 UTC

Mix-and-match synthesis of 3D small molecules
Nature, Published online: 02 April 2026; [doi:10.1038/d41586-026-00809-0][1]
Chemistry that forms an omnipresent type of carbon–carbon bond enables the modular synthesis of 3D organic molecules — a boon for drug discovery and materials design.
[1]: https://www.nature.com/articles/d41586-026-00809-0
https://www.nature.com/articles/d41586-026-00809-0

2026-03-31 15:30:40 UTC

Structure of the mouse cytoplasmic lattice
Nature, Published online: 31 March 2026; [doi:10.1038/s41586-026-10442-6][1]
Structure of the mouse cytoplasmic lattice
[1]: https://www.nature.com/articles/s41586-026-10442-6
https://www.nature.com/articles/s41586-026-10442-6

2026-03-31 09:29:32 UTC

AI used in warfare needs a strong ethical framework
Nature, Published online: 31 March 2026; [doi:10.1038/d41586-026-01008-7][1]
AI used in warfare needs a strong ethical framework
[1]: https://www.nature.com/articles/d41586-026-01008-7
https://www.nature.com/articles/d41586-026-01008-7

2026-03-31 09:29:27 UTC

A responsible authorship culture is needed — it is a collective responsibility
Nature, Published online: 31 March 2026; [doi:10.1038/d41586-026-00997-9][1]
A responsible authorship culture is needed — it is a collective responsibility
[1]: https://www.nature.com/articles/d41586-026-00997-9
https://www.nature.com/articles/d41586-026-00997-9

2026-03-31 09:29:22 UTC

Schrödinger’s carbon’: The misclassification of carbon capture and storage as standard mitigation
Nature, Published online: 31 March 2026; [doi:10.1038/d41586-026-01009-6][1]
Schrödinger’s carbon’: The misclassification of carbon capture and storage as standard mitigation
[1]: https://www.nature.com/articles/d41586-026-01009-6
https://www.nature.com/articles/d41586-026-01009-6

2026-03-31 09:29:16 UTC

Author Correction: Signatures of ambient pressure superconductivity in thin film La3Ni2O7
Nature, Published online: 31 March 2026; [doi:10.1038/s41586-026-10335-8][1]
Author Correction: Signatures of ambient pressure superconductivity in thin film La3Ni2O7
[1]: https://www.nature.com/articles/s41586-026-10335-8
https://www.nature.com/articles/s41586-026-10335-8

2026-03-31 08:29:24 UTC

The hidden costs of ‘helpful’ AI
Nature, Published online: 31 March 2026; [doi:10.1038/d41586-026-00966-2][1]
Even when artificial-intelligence tools aid individuals’ decision-making, they can quietly de-skill whole professions by narrowing how uncertainties and values are debated.
[1]: https://www.nature.com/articles/d41586-026-00966-2
https://www.nature.com/articles/d41586-026-00966-2

2026-03-30 15:34:22 UTC

Dawkins’s paradox: dissecting the body’s battle to keep selfish genes in check
Nature, Published online: 30 March 2026; [doi:10.1038/d41586-026-00970-6][1]
An essay series by specialists in evolutionary biology, philosophy and more examines the ‘paradox of the organism’.
[1]: https://www.nature.com/articles/d41586-026-00970-6
https://www.nature.com/articles/d41586-026-00970-6

2026-03-30 14:28:46 UTC

Inside the ‘self-driving’ lab revolution
Nature, Published online: 30 March 2026; [doi:10.1038/d41586-026-00974-2][1]
AI-powered robotic tools are muscling in on tasks typically done by humans. What does the future hold?
[1]: https://www.nature.com/articles/d41586-026-00974-2
https://www.nature.com/articles/d41586-026-00974-2

2026-03-30 14:28:41 UTC

Static electricity is a mystery but invisible carbon may be key
Nature, Published online: 30 March 2026; [doi:10.1038/d41586-026-01012-x][1]
A thin layer of carbon on the surface of oxide grains changes how they exchange static charge.
[1]: https://www.nature.com/articles/d41586-026-01012-x
https://www.nature.com/articles/d41586-026-01012-x

2026-03-30 13:26:51 UTC

Quantum simulations verified by experiments for the first time
Nature, Published online: 30 March 2026; [doi:10.1038/d41586-026-00959-1][1]
Physicists cross-checked quantum computer predictions against experimental data about materials' properties.
[1]: https://www.nature.com/articles/d41586-026-00959-1
https://www.nature.com/articles/d41586-026-00959-1

2026-03-30 13:26:45 UTC

Why I made a river my co-author
Nature, Published online: 30 March 2026; [doi:10.1038/d41586-026-00973-3][1]
Anne Poelina gives first authorship to a source with deep knowledge about water — the river itself.
[1]: https://www.nature.com/articles/d41586-026-00973-3
https://www.nature.com/articles/d41586-026-00973-3

2026-03-30 12:30:21 UTC

Anthony Leggett obituary: physicist who brought quantum theory to the macro world
Nature, Published online: 30 March 2026; [doi:10.1038/d41586-026-01010-z][1]
The polymath also trained as a philosopher and won a Nobel prize for his theory of superfluids.
[1]: https://www.nature.com/articles/d41586-026-01010-z
https://www.nature.com/articles/d41586-026-01010-z

2026-03-30 12:30:16 UTC

Countdown to Artemis: is NASA’s Moon mission the dawn of a new space age?
Nature, Published online: 30 March 2026; [doi:10.1038/d41586-026-00998-8][1]
As humans, we must be intentional about whether, and how, we explore space.
[1]: https://www.nature.com/articles/d41586-026-00998-8
https://www.nature.com/articles/d41586-026-00998-8

2026-03-30 11:26:19 UTC

Now is the time for scientific societies to guide global research
Nature, Published online: 30 March 2026; [doi:10.1038/d41586-025-04155-5][1]
Electrical engineer Ratko Magjarević explains the benefits of joining and leading scientific societies.
[1]: https://www.nature.com/articles/d41586-025-04155-5
https://www.nature.com/articles/d41586-025-04155-5

2026-03-30 11:26:14 UTC

How buildings and cities can be aligned with life
Nature, Published online: 30 March 2026; [doi:10.1038/d41586-026-00971-5][1]
Following nature’s patterns, not fighting them, is the way forward for the built environment.
[1]: https://www.nature.com/articles/d41586-026-00971-5
https://www.nature.com/articles/d41586-026-00971-5

2026-03-30 09:25:41 UTC

Dawkin’s paradox: dissecting the body’s battle to keep selfish genes in check
Nature, Published online: 30 March 2026; [doi:10.1038/d41586-026-00970-6][1]
An essay series by specialists in evolutionary biology, philosophy and more examines the ‘paradox of the organism’.
[1]: https://www.nature.com/articles/d41586-026-00970-6
https://www.nature.com/articles/d41586-026-00970-6

2026-03-27 23:15:06 UTC

Eye drops made from pig semen deliver cancer treatment to mice
Nature, Published online: 27 March 2026; [doi:10.1038/d41586-026-00982-2][1]
Minuscule particles with the ability to cross hard-to-penetrate barriers can be loaded with drug treatments to target intractable diseases.
[1]: https://www.nature.com/articles/d41586-026-00982-2
https://www.nature.com/articles/d41586-026-00982-2

2026-03-27 14:14:22 UTC

Briefing Chat: ‘Zombie cells’ resurrected with new genes
Nature, Published online: 27 March 2026; [doi:10.1038/d41586-026-00996-w][1]
Nature staff discuss some of the week's top science news.
[1]: https://www.nature.com/articles/d41586-026-00996-w
https://www.nature.com/articles/d41586-026-00996-w

2026-03-27 13:13:22 UTC

Motherhood derails women’s academic careers — these data reveal how and why
Nature, Published online: 27 March 2026; [doi:10.1038/d41586-026-00981-3][1]
Mothers in academia take on considerably more childcare-related responsibilities than do fathers.
[1]: https://www.nature.com/articles/d41586-026-00981-3
https://www.nature.com/articles/d41586-026-00981-3

2026-03-27 12:16:19 UTC

Giants of the deep and the wonder of space: Books in Brief
Nature, Published online: 27 March 2026; [doi:10.1038/d41586-026-00995-x][1]
Andrew Robinson reviews five of the best science picks.
[1]: https://www.nature.com/articles/d41586-026-00995-x
https://www.nature.com/articles/d41586-026-00995-x

2026-03-27 03:13:13 UTC

Sunken Soviet nuclear submarine’s radioactive release
Nature, Published online: 27 March 2026; [doi:10.1038/d41586-026-00953-7][1]
Low levels of radioactive strontium and caesium are emanating from a pipe on the wreck of the Komsomolets.
[1]: https://www.nature.com/articles/d41586-026-00953-7
https://www.nature.com/articles/d41586-026-00953-7

2026-03-27 03:13:08 UTC

Huge lung-cancer screening campaign boosts early diagnosis
Nature, Published online: 27 March 2026; [doi:10.1038/d41586-026-00954-6][1]
A programme that offers scans to smokers between the ages of 55 and 74 detects a large number of early-stage lung tumours.
[1]: https://www.nature.com/articles/d41586-026-00954-6
https://www.nature.com/articles/d41586-026-00954-6

2026-03-26 21:11:20 UTC

Chats with sycophantic AI make you less kind to others
Nature, Published online: 26 March 2026; [doi:10.1038/d41586-026-00979-x][1]
Even people who were sceptical of chatbots’ utility fell under the sway of the AI tools’ flattery.
[1]: https://www.nature.com/articles/d41586-026-00979-x
https://www.nature.com/articles/d41586-026-00979-x

2026-03-26 18:11:32 UTC

Trump’s new science advisers include 12 technology chiefs — and one academic
Nature, Published online: 26 March 2026; [doi:10.1038/d41586-026-00977-z][1]
Sparse academic presence on the US President’s Council of Advisors on Science and Technology reflects a focus on technology and industry.
[1]: https://www.nature.com/articles/d41586-026-00977-z
https://www.nature.com/articles/d41586-026-00977-z

2026-03-26 17:11:28 UTC

Why labs need a napping room to help you work, rest and play
Nature, Published online: 26 March 2026; [doi:10.1038/d41586-026-00549-1][1]
A 30-minute snooze can boost creativity and help banish burnout, says neuroscientist Joseph Jebelli, author of The Brain at Rest.
[1]: https://www.nature.com/articles/d41586-026-00549-1
https://www.nature.com/articles/d41586-026-00549-1

2026-03-26 01:13:15 UTC

History of ‘forever’ chemicals is written in Antarctic snow
Nature, Published online: 26 March 2026; [doi:10.1038/d41586-026-00867-4][1]
Data gathered during a 1,200-kilometre polar trek show where PFAS levels are the highest.
[1]: https://www.nature.com/articles/d41586-026-00867-4
https://www.nature.com/articles/d41586-026-00867-4

2026-03-25 21:08:40 UTC

First atlas of brain organization shows development over a lifetime
Nature, Published online: 25 March 2026; [doi:10.1038/d41586-026-00975-1][1]
Scans of more than 3,500 people allow scientists to draw up a guide to the brain areas that work together from birth to 100 years old.
[1]: https://www.nature.com/articles/d41586-026-00975-1
https://www.nature.com/articles/d41586-026-00975-1

2026-03-25 19:12:06 UTC

‘Grade inflation’ hits PhD students. What’s behind the increase?
Nature, Published online: 25 March 2026; [doi:10.1038/d41586-026-00952-8][1]
Study of one US university shows grades rising for master’s and PhD students over the past two decades.
[1]: https://www.nature.com/articles/d41586-026-00952-8
https://www.nature.com/articles/d41586-026-00952-8

2026-03-25 18:23:15 UTC

How to build an AI Scientist: first peer-reviewed paper spills the secrets
Nature, Published online: 25 March 2026; [doi:10.1038/d41586-026-00899-w][1]
AI Scientist, an autonomous research tool, first released in 2024, has now undergone peer review, highlighting its strengths and limitations.
[1]: https://www.nature.com/articles/d41586-026-00899-w
https://www.nature.com/articles/d41586-026-00899-w

2026-03-25 18:23:10 UTC

Who let the wolves in? Genetic record for domestic dogs pushed back by 5,000 years
Nature, Published online: 25 March 2026; [doi:10.1038/d41586-026-00900-6][1]
The oldest ancient dog genomes on record all come from a population that lived alongside Ice Age hunter-gatherers across Europe and the Middle East.
[1]: https://www.nature.com/articles/d41586-026-00900-6
https://www.nature.com/articles/d41586-026-00900-6

2026-03-25 18:23:04 UTC

Why insects aren't huge: a new challenge to a decades-old idea
Nature, Published online: 25 March 2026; [doi:10.1038/d41586-026-00976-0][1]
Evidence suggests oxygen levels may not have been limiting factor — plus, CRISPR gives cancer-fighting immune cells an upgrade.
[1]: https://www.nature.com/articles/d41586-026-00976-0
https://www.nature.com/articles/d41586-026-00976-0

2026-03-25 17:10:58 UTC

Extreme climate outcomes could still occur with just 2 °C of global warming
Nature, Published online: 25 March 2026; [doi:10.1038/d41586-026-00640-7][1]
Moderate global warming creates a risk of climate impacts that are more severe than the most-likely impacts of high global warming.
[1]: https://www.nature.com/articles/d41586-026-00640-7
https://www.nature.com/articles/d41586-026-00640-7

2026-03-25 17:10:52 UTC

Testosterone promotes growth of a type of brain tumour in young boys
Nature, Published online: 25 March 2026; [doi:10.1038/d41586-026-00638-1][1]
A type of childhood brain tumour called ependymoma is more common in boys than in girls. The reason for this difference turns out to be sex hormones such as testosterone.
[1]: https://www.nature.com/articles/d41586-026-00638-1
https://www.nature.com/articles/d41586-026-00638-1

2026-03-25 17:10:47 UTC

Pilot project paves way to storing CO2 underground as minerals in arid countries
Nature, Published online: 25 March 2026; [doi:10.1038/d41586-026-00635-4][1]
Carbon dioxide has been turned into minerals in Earth’s subsurface using recirculating water flow — a viable way to sequester this greenhouse gas in water-scarce areas.
[1]: https://www.nature.com/articles/d41586-026-00635-4
https://www.nature.com/articles/d41586-026-00635-4

2026-03-25 17:10:42 UTC

AI scientists are changing research — institutions, funders and publishers must respond
Nature, Published online: 25 March 2026; [doi:10.1038/d41586-026-00934-w][1]
The ability to automate the discovery process in some areas of scientific inquiry raises unanswered questions about how research should be conducted.
[1]: https://www.nature.com/articles/d41586-026-00934-w
https://www.nature.com/articles/d41586-026-00934-w

2026-03-25 17:10:37 UTC

Dogs have deep genetic roots in ice-age Europe
Nature, Published online: 25 March 2026; [doi:10.1038/d41586-026-00378-2][1]
Two studies report the oldest dog genomes ever to be sequenced, representing leaps in scientists’ understanding of the animal’s origins.
[1]: https://www.nature.com/articles/d41586-026-00378-2
https://www.nature.com/articles/d41586-026-00378-2

2026-03-25 17:10:32 UTC

Long-distance quantum link generates entanglement faster than it is lost
Nature, Published online: 25 March 2026; [doi:10.1038/d41586-026-00804-5][1]
Entanglement between ions connected by 10 kilometres of optical fibre is a step towards large-scale quantum communications networks.
[1]: https://www.nature.com/articles/d41586-026-00804-5
https://www.nature.com/articles/d41586-026-00804-5

2026-03-25 17:10:26 UTC

Charting the human brain’s lifelong functional organization
Nature, Published online: 25 March 2026; [doi:10.1038/d41586-026-00637-2][1]
Neuroscientists have created a continuous atlas showing how patterns of functional connectivity between brain regions change from birth to old age.
[1]: https://www.nature.com/articles/d41586-026-00637-2
https://www.nature.com/articles/d41586-026-00637-2

2026-03-25 17:10:21 UTC

A cancer-promoting fusion protein acts during embryonic brain development
Nature, Published online: 25 March 2026; [doi:10.1038/d41586-026-00924-y][1]
ZFTA–RELA is the cancer-promoting protein product of a gene fusion. Analyses of accessible sites in the DNA–protein complex chromatin in developing mice show that ZFTA–RELA binds to chromatin modules that are accessible during embryonic brain development, placing some cell lineages at risk of transformation into cancer.
[1]: https://www.nature.com/articles/d41586-026-00924-y
https://www.nature.com/articles/d41586-026-00924-y

2026-03-25 17:10:16 UTC

Anticancer antibodies can evolve to cause autoimmune brain disease
Nature, Published online: 25 March 2026; [doi:10.1038/d41586-026-00919-9][1]
A model of breast cancer that expresses NMDA receptors — proteins that modify signalling between neurons — was used to trace pre-existing B cells as they matured to produce autoimmune antibodies that have diverse effects on receptor function. Transferring one antibody into mouse brains recapitulated key features of autoimmune brain inflammation.
[1]: https://www.nature.com/articles/d41586-026-00919-9
https://www.nature.com/articles/d41586-026-00919-9

2026-03-25 17:10:11 UTC

Remembrance of inflammations past
Nature, Published online: 25 March 2026; [doi:10.1038/d41586-026-00639-0][1]
Chronic inflammation increases the risk of colon cancer. This inflammation drives epigenetic changes in the nucleus of stem cells that promote tumour formation.
[1]: https://www.nature.com/articles/d41586-026-00639-0
https://www.nature.com/articles/d41586-026-00639-0

2026-03-25 17:10:05 UTC

Redirecting current solves a shadowy problem faced by perovskite solar cells
Nature, Published online: 25 March 2026; [doi:10.1038/d41586-026-00921-1][1]
Solar modules made from perovskite materials have a stability issue that arises when they are placed in partial shade. This long-standing problem has now been addressed by integrating an electronic component called a memristor into the solar cell.
[1]: https://www.nature.com/articles/d41586-026-00921-1
https://www.nature.com/articles/d41586-026-00921-1

2026-03-25 17:10:00 UTC

Superluminal correlations in ensembles of optical phase singularities
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10209-z][1]
Ultrafast electron imaging shows full phase-space dynamics of optical singularities, which can reach superluminal velocities before annihilation and break the particle-like analogy of topological defects.
[1]: https://www.nature.com/articles/s41586-026-10209-z
https://www.nature.com/articles/s41586-026-10209-z

2026-03-25 17:09:55 UTC

Moderate global warming does not rule out extreme global climate outcomes
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10237-9][1]
Extreme global climate outcomes may occur even under moderate 2 °C warming and may turn out to be more extreme than model-averaged projections at 3 °C or 4 °C warming.
[1]: https://www.nature.com/articles/s41586-026-10237-9
https://www.nature.com/articles/s41586-026-10237-9

2026-03-25 17:09:50 UTC

Decadal-scale droughts disrupted the African Humid Period in the Sahara
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10336-7][1]
Sedimentary time-series data of Lake Yoa in Chad covering the past 10.25 thousand years (kyr) show that the mid-Holocene African Humid Period experienced several decadal-scale droughts, caused by sudden inputs of freshwater into the North Atlantic.
[1]: https://www.nature.com/articles/s41586-026-10336-7
https://www.nature.com/articles/s41586-026-10336-7

2026-03-25 17:09:44 UTC

Oxygen supply through the tracheolar–muscle system does not constrain insect gigantism
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10291-3][1]
New evidence suggests that diffusive oxygen transport through the tracheolar–muscle system is not the limiting factor on insect body size.
[1]: https://www.nature.com/articles/s41586-026-10291-3
https://www.nature.com/articles/s41586-026-10291-3

2026-03-25 17:09:39 UTC

Quantifying climate loss and damage consistent with a social cost of carbon
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10272-6][1]
A new framework links specific emissions to monetized, location-specific climate damages, showing that future harms from past CO2 emissions far exceed historical damages and that delayed carbon removal cannot fully offset these losses.
[1]: https://www.nature.com/articles/s41586-026-10272-6
https://www.nature.com/articles/s41586-026-10272-6

2026-03-25 17:09:34 UTC

Precipitation observing network gaps limit climate change impact assessment
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10300-5][1]
At present, only 13.4% of the global land surface meets the World Meteorological Organization requirements for annual precipitation monitoring.
[1]: https://www.nature.com/articles/s41586-026-10300-5
https://www.nature.com/articles/s41586-026-10300-5

2026-03-25 17:09:29 UTC

Disequilibrium response to tapping crustal magma reveals storage conditions
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10317-w][1]
Magma drilling data from Krafla volcano, Iceland, are used to reconstruct in situ lithostatic magmatic conditions using disequilibrium simulations that provide a method for improving the understanding of magma storage conditions and evolution.
[1]: https://www.nature.com/articles/s41586-026-10317-w
https://www.nature.com/articles/s41586-026-10317-w

2026-03-25 17:09:24 UTC

Towards end-to-end automation of AI research
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10265-5][1]
An artificial intelligence system can produce research papers with minimal human involvement, even passing the first round of peer review for the workshop of a main machine learning conference.
[1]: https://www.nature.com/articles/s41586-026-10265-5
https://www.nature.com/articles/s41586-026-10265-5

2026-03-25 17:09:18 UTC

Epigenetic memory of colitis promotes tumour growth
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10258-4][1]
Colonic stem cells retain a memory of inflammation following disease resolution and there is a mechanistic link between chronic inflammation and malignancy, suggesting potential strategies to mitigate cancer risk in patients with chronic inflammatory conditions.
[1]: https://www.nature.com/articles/s41586-026-10258-4
https://www.nature.com/articles/s41586-026-10258-4

2026-03-25 17:09:13 UTC

Parasites trigger epithelial cell crosstalk to drive gut–brain signalling
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10281-5][1]
Paracrine signalling between tuft cells and enterochromaffin cells is a key mode of immune–sensory and gut–brain communication, and accounts for the pattern of gastrointestinal symptoms that occurs during parasite infections.
[1]: https://www.nature.com/articles/s41586-026-10281-5
https://www.nature.com/articles/s41586-026-10281-5

2026-03-25 17:09:08 UTC

Electrochemical corrosion accompanies dendrite growth in solid electrolytes
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10279-z][1]
Operando birefringence microscopy measurements of the stresses around growing dendrites in solid electrolytes show that stresses decrease as current densities increase, revealing a linkage between electrochemical and mechanical stability that informs the design of solid-state batteries.
[1]: https://www.nature.com/articles/s41586-026-10279-z
https://www.nature.com/articles/s41586-026-10279-z

2026-03-25 17:09:03 UTC

CO2 subsurface mineral storage by its co-injection with recirculating water
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10130-5][1]
An industrial-scale pilot project using co-injection of recirculated water for subsurface CO2 mineralization shows promise as a pathway for carbon sequestration in regions with limited access to water resources.
[1]: https://www.nature.com/articles/s41586-026-10130-5
https://www.nature.com/articles/s41586-026-10130-5

2026-03-25 17:08:58 UTC

Dogs were widely distributed across western Eurasia during the Palaeolithic
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10170-x][1]
Analysis of nuclear and mitochondrial genomes from archaeological canid remains found across Europe and Anatolia shows that a genetically homogeneous dog population was already widely distributed across the region by 15,000 years ago.
[1]: https://www.nature.com/articles/s41586-026-10170-x
https://www.nature.com/articles/s41586-026-10170-x

2026-03-25 17:08:52 UTC

Structural basis of supercoiling-induced CRISPR–Cas9 off-target activity
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10255-7][1]
Cas9 structures explain topology sensing and off-target activation.
[1]: https://www.nature.com/articles/s41586-026-10255-7
https://www.nature.com/articles/s41586-026-10255-7

2026-03-25 17:08:47 UTC

Rapid concerted switching of the neural code in the inferotemporal cortex
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10267-3][1]
Face cells in the macaque inferotemporal cortex are initially able to detect faces and then rapidly switch to a face-specific neural code to discriminate between different face identities.
[1]: https://www.nature.com/articles/s41586-026-10267-3
https://www.nature.com/articles/s41586-026-10267-3

2026-03-25 17:08:42 UTC

The DNA virome varies with human genes and environments
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10288-y][1]
Analyses of biobank data show that human variation such as age, sex and genetics, particularly at the major histocompatibility complex locus, is associated with viral abundance and supports a causal link between abundance of Epstein–Barr virus and Hodgkin’s lymphoma.
[1]: https://www.nature.com/articles/s41586-026-10288-y
https://www.nature.com/articles/s41586-026-10288-y

2026-03-25 17:08:37 UTC

Androgen activity in the male embryonic hindbrain drives lethal PFA ependymoma
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10264-6][1]
Androgen activity in the male embryonic hindbrain prolongs hindbrain differentiation in male individuals and drives sex differences in the incidence and prognosis of posterior fossa type A (PFA) ependymoma, an aggressive childhood brain tumour.
[1]: https://www.nature.com/articles/s41586-026-10264-6
https://www.nature.com/articles/s41586-026-10264-6

2026-03-25 17:08:32 UTC

A fast starburst wind consumes most of the energy from supernovae
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10231-1][1]
Starburst galaxies are seen to host galaxy-scale winds, which are super-fast and could be powered entirely by the thermal pressure of gas heated by supernovae.
[1]: https://www.nature.com/articles/s41586-026-10231-1
https://www.nature.com/articles/s41586-026-10231-1

2026-03-25 17:08:27 UTC

Structural energetics of cold sensitivity
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10276-2][1]
Data from cryogenic electron microscopy combined with hydrogen–deuterium exchange mass spectrometry inform a mechanism for cold-evoked activation of the TRPM8 channel, providing a structural and energetic framework to explain cold sensitivity.
[1]: https://www.nature.com/articles/s41586-026-10276-2
https://www.nature.com/articles/s41586-026-10276-2

2026-03-25 17:08:21 UTC

Topological soliton frequency comb in nanophotonic lithium niobate
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10292-2][1]
An integrated lithium niobate–semiconductor platform generates topological soliton frequency combs on-chip, enabling turn-key, dispersion-agnostic comb sources without high-Q resonators or complex stabilization.
[1]: https://www.nature.com/articles/s41586-026-10292-2
https://www.nature.com/articles/s41586-026-10292-2

2026-03-25 17:08:16 UTC

Inactivating SnRK1β1A promotes broad-spectrum disease resistance in rice
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10273-5][1]
SnRK1β1A in rice promotes susceptibility to multiple fungal diseases, and disrupting this infection-inducible gene confers broad-spectrum resistance without compromising growth or yield under normal field conditions.
[1]: https://www.nature.com/articles/s41586-026-10273-5
https://www.nature.com/articles/s41586-026-10273-5

2026-03-25 17:08:11 UTC

Aversive learning hijacks a brain sugar sensor to consolidate memory
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10306-z][1]
A study in Drosophilareveals a mechanism of non-homeostatic hunger and its critical relevance for memory consolidation.
[1]: https://www.nature.com/articles/s41586-026-10306-z
https://www.nature.com/articles/s41586-026-10306-z

2026-03-25 17:08:06 UTC

Towards intelligent and miniaturized drug delivery devices
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10221-3][1]
Intelligent and miniaturized drug delivery devices leveraging advances in biotechnology, artificial intelligence, electronics and materials science enable treatments with increased precision and responsiveness, with applications in cancer, diabetes, cardiovascular disease and other diseases.
[1]: https://www.nature.com/articles/s41586-026-10221-3
https://www.nature.com/articles/s41586-026-10221-3

2026-03-25 17:08:00 UTC

Functional hierarchy of the human neocortex across the lifespan
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10219-x][1]
fMRI data from individuals of a wide range of ages (from a few days to 100 years old) are used to map the key organizational axes of functional connectivity in the human cortex throughout the lifespan.
[1]: https://www.nature.com/articles/s41586-026-10219-x
https://www.nature.com/articles/s41586-026-10219-x

2026-03-25 17:07:55 UTC

Exposed phosphatidylserine is an inhibitory molecule in T cell exhaustion
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10266-4][1]
Insights into the mechanism by which phosphatidylserine functions as a non-classical inhibitory molecule during T cell exhaustion, and how phosphatidylserine-targeting antibodies enhance T cell responses are explored.
[1]: https://www.nature.com/articles/s41586-026-10266-4
https://www.nature.com/articles/s41586-026-10266-4

2026-03-25 17:07:50 UTC

Ectopic NMDAR expression in cancer unmasks germline-encoded autoimmunity
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10278-0][1]
NMDAR expression is sufficient to induce B cell recruitment and affinity maturation, resulting in receptor-modulating antibodies that connect anti-cancer immunity and autoimmunity.
[1]: https://www.nature.com/articles/s41586-026-10278-0
https://www.nature.com/articles/s41586-026-10278-0

2026-03-25 17:07:45 UTC

Dominant clones leverage developmental epigenomic states to drive ependymoma
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10270-8][1]
Single-nucleus chromatin and RNA sequencing identifies epigenetic chromatin domains that confer vulnerability to paediatric brain tumours such as ependymomas, providing insight into the development of such tumours despite ‘quiet’ genomes.
[1]: https://www.nature.com/articles/s41586-026-10270-8
https://www.nature.com/articles/s41586-026-10270-8

2026-03-25 17:07:40 UTC

Genomic history of early dogs in Europe
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10112-7][1]
Genome-wide analysis shows European dogs existed by 14,200 years ago, were already genetically distinct, received less Neolithic Southwest Asian admixture than humans did and contributed substantially to later European dogs.
[1]: https://www.nature.com/articles/s41586-026-10112-7
https://www.nature.com/articles/s41586-026-10112-7

2026-03-25 17:07:34 UTC

Retraction Note: Multisensory learning binds neurons into a cross-modal memory engram
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10355-4][1]
Retraction Note: Multisensory learning binds neurons into a cross-modal memory engram
[1]: https://www.nature.com/articles/s41586-026-10355-4
https://www.nature.com/articles/s41586-026-10355-4

2026-03-25 15:17:35 UTC

Geopolitical tensions are leading China to rethink research collaboration
Nature, Published online: 25 March 2026; [doi:10.1038/d41586-026-00426-x][1]
A shift to regional partnerships and use of tightly controlled platforms suggests openness is being designed and managed.
[1]: https://www.nature.com/articles/d41586-026-00426-x
https://www.nature.com/articles/d41586-026-00426-x

2026-03-25 15:17:30 UTC

The pros and cons of China’s health role in Africa
Nature, Published online: 25 March 2026; [doi:10.1038/d41586-026-00425-y][1]
Funds and expertise are a welcome boost, but questions remain about balanced cooperation.
[1]: https://www.nature.com/articles/d41586-026-00425-y
https://www.nature.com/articles/d41586-026-00425-y

2026-03-25 15:17:25 UTC

A guide to the Nature Index
Nature, Published online: 25 March 2026; [doi:10.1038/d41586-026-00427-w][1]
A description of the terminology and methodology used in this supplement, and a guide to the functionality that is available free online at natureindex.com.
[1]: https://www.nature.com/articles/d41586-026-00427-w
https://www.nature.com/articles/d41586-026-00427-w

2026-03-25 15:17:19 UTC

Why China’s philanthropists are digging deep for research
Nature, Published online: 25 March 2026; [doi:10.1038/d41586-026-00424-z][1]
An increase in donations, prizes and public–private initiatives suggests many firms want to show commitment to the government’s goals.
[1]: https://www.nature.com/articles/d41586-026-00424-z
https://www.nature.com/articles/d41586-026-00424-z

2026-03-25 15:17:14 UTC

China is an innovation powerhouse — but it should do more fundamental research
Nature, Published online: 25 March 2026; [doi:10.1038/d41586-026-00935-9][1]
As the country looks to commercial companies to drive innovation, it has a golden opportunity to support open science and increase its output in key areas.
[1]: https://www.nature.com/articles/d41586-026-00935-9
https://www.nature.com/articles/d41586-026-00935-9

2026-03-25 15:17:09 UTC

Can China keep up its extraordinary research growth?
Nature, Published online: 25 March 2026; [doi:10.1038/d41586-026-00423-0][1]
Evidence of a pivot towards other sources of funding and collaboration suggest it is looking for ways to maintain its rapid pace of change.
[1]: https://www.nature.com/articles/d41586-026-00423-0
https://www.nature.com/articles/d41586-026-00423-0

2026-03-25 14:07:28 UTC

Sock. Something. Um.
Nature, Published online: 25 March 2026; [doi:10.1038/d41586-026-00614-9][1]
A fair exchange?
[1]: https://www.nature.com/articles/d41586-026-00614-9
https://www.nature.com/articles/d41586-026-00614-9

2026-03-25 12:06:35 UTC

‘Continuity over novelty’: why environmental science needs to rethink its focus
Nature, Published online: 25 March 2026; [doi:10.1038/d41586-026-00933-x][1]
With government funding in decline, researchers should prioritize data collation and training the next generation of scientists.
[1]: https://www.nature.com/articles/d41586-026-00933-x
https://www.nature.com/articles/d41586-026-00933-x

2026-03-25 12:06:20 UTC

Major conference catches illicit AI use — and rejects hundreds of papers
Nature, Published online: 25 March 2026; [doi:10.1038/d41586-026-00893-2][1]
The papers’ watermarks allowed organizers to detect use of large language models in peer review.
[1]: https://www.nature.com/articles/d41586-026-00893-2
https://www.nature.com/articles/d41586-026-00893-2