nprofile1qy2hwumn8ghj7un9d3shjtnyd968gmewwp6kyqpqkedxdacmlj8utzpdv2ud46d72gyzac6v0y3u2e2g596umumzdwrq5dhrzl (nprofile…hrzl) It is frowned upon as it may cause weird things to happen depending on what current is going to flow in that connection.
If you don't populate this component your ground will be broken. This you typically find after hours of debugging.
Unless you need a simple pull-down on the other side don't do it.