To do this, they wanted to make a chemical with two faces one that bound the quality control system and one that bound the protein they wanted to destroy. Both are difficult chemistries to build.
But the work on thalidomide revealed a ready made chemical that bound the quality control system, this spurred a whole ton of academic and biotech research that is just now bearing its first fruits.
5/🧵
MCDuncanLab
npub14k…6yep4
2026-05-10 13:04:09 UTC
in reply to nevent1q…57w0
Author Public Key
npub14k3sv7gtyhujmep00nkx86m4h6yv2rsna740rasupl93h00d2fvq26yep4Seen on
wss://relay.momostr.pinkPublished at
2026-05-10 13:04:09 UTCEvent JSON
{
"id": "d77c4b70d0cf6d37d683e94c069565ea2a124f7ff4a7b2d571bc3fcf2b6652db",
"pubkey": "ada306790b25f92de42f7cec63eb75be88c50e13efaaf1f61c0fcb1bbded5258",
"created_at": 1778418249,
"kind": 1,
"tags": [
[
"p",
"ada306790b25f92de42f7cec63eb75be88c50e13efaaf1f61c0fcb1bbded5258"
],
[
"e",
"4309ae65b084978ca9bc25abbc04264647ece291289b0fb25509c799d395f944",
"",
"root",
"ada306790b25f92de42f7cec63eb75be88c50e13efaaf1f61c0fcb1bbded5258"
],
[
"e",
"f016e1e549c7b11fcf7ef41173b05269de21d4c9c7672c2f3291c1beac5ffb5d",
"",
"reply",
"ada306790b25f92de42f7cec63eb75be88c50e13efaaf1f61c0fcb1bbded5258"
],
[
"proxy",
"https://mstdn.social/@MCDuncanLab/116550418393356397",
"web"
],
[
"proxy",
"https://mstdn.social/users/MCDuncanLab/statuses/116550418393356397",
"activitypub"
],
[
"L",
"pink.momostr"
],
[
"l",
"pink.momostr.activitypub:https://mstdn.social/users/MCDuncanLab/statuses/116550418393356397",
"pink.momostr"
],
[
"-"
]
],
"content": "To do this, they wanted to make a chemical with two faces one that bound the quality control system and one that bound the protein they wanted to destroy. Both are difficult chemistries to build.\n\nBut the work on thalidomide revealed a ready made chemical that bound the quality control system, this spurred a whole ton of academic and biotech research that is just now bearing its first fruits.\n\n5/🧵",
"sig": "ed557285c42797848a8629ff8bd2e93168b05325dad13b3b5736e5193c664ffa7922d43fefccede6625242828230c31ba52ff0a25c4de82eaf3dafc4a4d85039"
}