PLOS Biology

PLOS Biology is the PLOS flagship journal in the life sciences. We are a selective, open-access, not-for-profit, peer-reviewed journal aiming to help advance discovery, depressurize the publication process and drive open science

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npub18ezux8xlhu0nsmp52eevhj03hc4tu7f3cfqwn97slyy6p52zgnyqg3mzt8

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PLOSBiology@fediscience-org.mostr.pub

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nprofile1qqsru3wrrn0m78ecds69vukte8cmu2470ycuys8fjlg0jzdq69pyfjqpz3mhxue69uhhyetvv9ujuerpd46hxtnfduqs6amnwvaz7tmwdaejumr0dsh3k4pj

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offchain.pub

relay.damus.io

nos.lol

Author Public Key

npub18ezux8xlhu0nsmp52eevhj03hc4tu7f3cfqwn97slyy6p52zgnyqg3mzt8

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Last Notes

2026-05-01 11:18:27 UTC

Adopting novel food is vital to colonize novel environments, but what is the role of social learning? Study of urban #cockatoos by shows them to rapidly adopt novel food via #SocialLearning, with juveniles showing conformist preferences @nprofile…nznc https://plos.io/4uq6NVq
https://fediscience.org/system/media_attachments/files/116/499/041/466/917/265/original/24146b969306eec3.jpg

2026-04-22 06:20:09 UTC

Bats harbor many #zoonotic #viruses yet remain asymptomatic; why? @nprofile…m2w5 &co show that #bat GBP5 evolved under +ve selection, driving virus-specific restriction & lineage-specific loss of a #prenylation motif that reshaped #antiviral function @nprofile…nznc https://plos.io/48KVgYe
https://fediscience.org/system/media_attachments/files/116/446/887/927/671/444/original/5ee6a99407dd511d.jpg

2026-04-15 08:59:41 UTC

Do animals have a favored tempo for communicating with each other? This study reveals a hotspot of 0.5-4 Hz for #communication across distinct species & modalities, hypothesizing that this may driven by biophysical commonalities of the receivers' #neurons @nprofile…nznc https://plos.io/4ccWuhh
https://fediscience.org/system/media_attachments/files/116/407/898/759/682/536/original/37a157cf8d203b01.jpg

2026-04-02 09:05:48 UTC

#SARSCoV2 has evolved to optimize its replication fitness in the human host. This study shows that a #nucleocapsid gene mutation enhances production of a truncated protein that boosts viral fitness by suppressing #antiviral responses @nprofile…nznc https://plos.io/3PIZMjr
https://fediscience.org/system/media_attachments/files/116/334/311/012/704/771/original/214598373e9d133b.jpg

2026-03-24 10:26:16 UTC

- reply

@nprofile…63pg Here you go! https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3003671
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3003686

2026-03-20 18:09:58 UTC

While it's tempting to suppose that everything that happens inside our cells has a function, Laurence Hurst explores a study in @nprofile…nznc showing that the high diversity of transcripts in mammals is down to the fact that accidents happen... Paper: plos.io/3Pcs2e6 Primer: plos.io/47Go2J2

2026-02-27 15:26:00 UTC

In support of #OpenScience, we routinely ask authors to openly share their #research #code before publication.
We are now formalizing this practice with a mandatory #code-sharing policy and clarifying what we mean by code sharing.
Useful to cut-out the box for future reference
https://plos.io/47dPeOW
https://fediscience.org/system/media_attachments/files/116/143/288/492/749/984/original/2ec168b02dcbf42c.png

2025-02-26 19:40:32 UTC

When did the lubricated joints that allow our skeleton to swivel, rotate and bend evolve? Gage Crump explores a new #plosbiology paper by @nprofile…yvg2 @nprofile…9rr5 &co that pinpoints their origin to the earliest jawed vertebrates. Paper: https://plos.io/3CTC8La Primer: https://plos.io/4kkhXa6
https://fediscience.org/system/media_attachments/files/114/071/884/214/790/394/original/e5327d1d731b37fd.jpg

2024-09-17 12:11:56 UTC

Refeeding after #fasting can lead to a "#FatOvershoot." @goldstein_lab @cumminslab &co examine the kinetics of #refeeding-induced transcriptional & chromatin changes, revealing a #lipogenic overshoot program regulated by the TF LXRα #PLOSBiology https://plos.io/4eukvi5
https://fediscience.org/system/media_attachments/files/113/152/826/719/536/197/original/704069d1943d8930.jpg

2024-03-12 15:07:14 UTC

Selective attention enables separation of overlapping speech in noisy environments. This study shows that #attention triggers bidirectional informational flow from #sensory regions to regions associated with semantic, syntactic & executive functions during active processing of #CocktailParty speech #PLOSBiology https://plos.io/3uZKBse
https://fediscience.org/system/media_attachments/files/112/083/337/480/639/780/original/ce9aad1cbb2865e8.jpg

2024-03-12 14:47:59 UTC

#ProteinQC pathways play key roles in resistance to #pathogens. @manishgrover_4 @barkoulab &co show that #proteasome regulation keeps #InnateImmune responses against natural pathogens of #Celegans in check in a tissue-specific manner #PLOSBiology https://plos.io/3PhIjLW
https://fediscience.org/system/media_attachments/files/112/083/263/672/511/879/original/f5912f0fd8db38a0.jpg

2024-03-12 14:30:25 UTC

#Bacteria have a #DNAdamage response to aberrant #DNAmethylation, but how do they sense this damage? @Aditya_Kamat96 @Tung_BK_Le @dnarepairlab &co describe a TF that regulates a methylation-specific DNA damage response in #Caulobacter #PLOSBiology https://plos.io/3v7pdkD
https://fediscience.org/system/media_attachments/files/112/083/194/546/454/021/original/4c17546547836769.jpg

2023-09-15 13:39:17 UTC

A novel TOX3-WDR5-H3K4me3/ABCG2 signaling axis is upregulated in #ColorectalCancer (CRC) #StemCells; these proteins may act as biomarkers for predicting CRC survival, and targets for countering drug tolerance, recurrence & #metastasis #PLOSBiology https://plos.io/3ZliKgx
https://fediscience.org/system/media_attachments/files/111/069/438/390/726/444/original/21d0d32cd0834e2e.jpg

2023-09-15 08:13:15 UTC

#Aspergillus fumigatus, a saprotrophic #fungus that can cause serious life-threatening invasive infections, smashes the record for number of meiotic crossovers... ~30 per #chromosome (>2x the previous record holder) @TheRedBen @EvelineSnelders #PLOSBiology https://plos.io/3rc3k1L
https://fediscience.org/system/media_attachments/files/111/068/157/525/157/142/original/10340de526cec5ca.jpg

2023-09-04 08:26:16 UTC

Comparing cytoarchitectural subdivisions of #BrocasArea in humans & #chimps: @gagdiez @FriedericiLab &co find that BA44 expanded from a purely action region to a bipartite system (action-related posterior & #syntax-related anterior) in humans #PLOSBiology https://plos.io/45D1tSq
https://fediscience.org/system/media_attachments/files/111/005/923/749/556/471/original/f27726e72f57c445.jpg

2023-09-01 09:22:58 UTC

Costly expression of #virulence factors by #Salmonella elicits gut inflammation, which in turn promotes #pathogen blooms. This study explains the tight connection between #microbiome complexity & evolution of Salmonella virulence #PLOSBiology https://plos.io/44BbHSb
https://fediscience.org/system/media_attachments/files/110/989/159/732/316/617/original/7de6fa5986c48d4d.jpg

2023-09-01 09:09:45 UTC

.@SarinayElif &co reveal a novel mechanism of growth coordination in #Celegans; inhibition of #ribosome biogenesis in epidermis can trigger organism-wide #GrowthQuiescence, potentially via secreted proteins & the dense-core vesicle pathway #PLOSBiology https://plos.io/3R1jYvq
https://fediscience.org/system/media_attachments/files/110/989/107/803/509/138/original/4cab0f1478c24211.jpg

2023-09-01 08:47:32 UTC

The excitation/inhibition ratio (E/I) may contribute to #MentalHealth, #cognition & #learning. @NienkevanBueren &co reveal that the E/I ratio in the brain plays a major role in neurostimulation efficacy and is a possible marker for learning #PLOSBiology https://plos.io/3Enavaa
https://fediscience.org/system/media_attachments/files/110/989/020/428/053/296/original/95a60a1ccb288ec0.jpg

2023-09-01 08:30:15 UTC

How do new #TasteBud cells connect with a taste ganglion #neuron? @ZacharyWhiddon1 @Krimmlab &co use in vivo 2-photon microscopy to observe motility & branching of taste axon arbors, revealing remarkable structural plasticity in taste buds #PLOSBiology https://plos.io/3PlIRAH
https://fediscience.org/system/media_attachments/files/110/988/952/475/173/217/original/1ba1b7051c857249.jpg

2023-09-01 08:21:46 UTC

Unprecedented nanometer-scale structures of cristae in >400 individual #mitochondria, by @Hirabayashi_Lab, using a novel deep learning-based analysis of #volumeEM images, (also reveals previously unknown function of OPA1) #PLOSBiology https://plos.io/3OXtPzK
https://fediscience.org/system/media_attachments/files/110/988/918/708/234/103/original/27ec8316925fd141.jpg

2023-09-01 08:18:48 UTC

#DendriticSpines contain a specialized ER, required for Ca2+ signaling, spine enlargement & #SynapticPlasticity. @yipinghsueh &co show that KLHL17 & SYNPO control the synaptic distribution of the ER, and so regulate synaptic plasticity #PLOSBiology https://plos.io/45PMrbR
https://fediscience.org/system/media_attachments/files/110/988/907/420/522/713/original/5a4f4e32507150e7.jpg

2023-08-15 18:07:53 UTC

"A brick in the wall": reconstruction of a @PinkFloyd song from recorded neural activity, revealing involvement of the #SuperiorTemporalGyrus in information processing during #MusicPerception. Implications for #BrainComputerInterface #PLOSBiology https://plos.io/47zOgve
https://fediscience.org/system/media_attachments/files/110/894/964/482/999/817/original/a45a64c6337f8cf6.jpg

2023-08-09 11:49:20 UTC

.@michele_studer &co show that the fate determinant transcription factor Fezf2 synergizes with the co-adaptor Lmo4 to reprogram upper layer cortical #neurons or postnatal #glia cells into corticofugal projection neurons #PLOSBiology https://plos.io/3ONxdOG
https://fediscience.org/system/media_attachments/files/110/859/502/100/611/185/original/461d0264fcdf0ff2.jpg

2023-08-04 16:57:17 UTC

Mutations in PARK15/FBXO7 cause #ParkinsonsDisease. @alsanchezmar @Aitor_Mtz & @whitworth_lab shows that its fly ortholog works antagonistically with USP30 to set the #ubiquitination threshold needed to regulate basal #mitophagy #PLOSBiology https://plos.io/3qfaUZ1
https://fediscience.org/system/media_attachments/files/110/832/401/530/485/812/original/ba5cdbb938b0fa8f.jpg

2023-08-04 16:45:14 UTC

Interaction between components of #MicrotubuleOrganizingCenters & #NuclearPores (Bfa1/Bub2 & Nup159) that facilitates autophagic degradation of a pool of #nucleoporin complexes and may favor specific elimination in the daughter cell @FMC_lab #PLOSBiology https://plos.io/45gNH7q
https://fediscience.org/system/media_attachments/files/110/832/353/993/137/556/original/507743c53e2daabf.jpg

2023-07-28 08:24:13 UTC

Honey #bees & social #wasps independently evolved hexagonal nest cells, but how to join large & small hexes? @SmithBeeLab show that despite different building materials & comb configs, they reach the same solution (A: pentagons + heptagons!) #PLOSBiology https://plos.io/453NowN
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