"HuR is a crucial regulator of glutaminase RNA metabolism in breast cancer that affects different aspects of mRNA metabolism, such as mRNA stability and splicing. Overall, HuR coordinates glutamine metabolism through the TCA cycle, and its depletion renders cells more dependent on glutamine for growth and migration and more sensitive to glutaminase inhibition."
https://www.nature.com/articles/s41467-024-49874-x#Sec10
Thiago Carvalho /
npub1xa…czham
2024-07-15 08:03:22
Author Public Key
npub1xakev87fgm9edqu6f5jhszwunekjxl3dpnq4sxvm3nzu2ace8xnqyczhamPublished at
2024-07-15 08:03:22Event JSON
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"content": "\"HuR is a crucial regulator of glutaminase RNA metabolism in breast cancer that affects different aspects of mRNA metabolism, such as mRNA stability and splicing. Overall, HuR coordinates glutamine metabolism through the TCA cycle, and its depletion renders cells more dependent on glutamine for growth and migration and more sensitive to glutaminase inhibition.\"\n\nhttps://www.nature.com/articles/s41467-024-49874-x#Sec10",
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