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Ectopic NMDAR expression in cancer unmasks germline-encoded autoimmunity

Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10278-0][1]

NMDAR expression is sufficient to induce B cell recruitment and affinity maturation, resulting in receptor-modulating antibodies that connect anti-cancer immunity and autoimmunity.

[1]: https://www.nature.com/articles/s41586-026-10278-0


https://www.nature.com/articles/s41586-026-10278-0