It depends on the nature of the theory.
Suppose the theory is that all unmarried men are bachelors, or that 2+2=4, or (to take an actual example from Mises) that human action is aimed at some goal.
Can you imagine an experiment that could disprove any of these?
On the other hand, suppose the theory is that an electron has a certain mass, or that ice melts at a certain temperature and pressure. It is very easy to imagine an experiment that might disprove such a theory.