NEW: Have acute appendicitis? To the OR… not so fast.
10-year RCT data (APPAC) show antibiotics alone work for many with uncomplicated disease:
• ~56% avoided surgery
• Recurrence ~38%
• MUCH fewer complications (8.5% vs 27.4% with surgery)
Appendectomy isn’t the only answer anymore. #press #EvidenceBased #evidencebased #press https://jamanetwork.com/journals/jama/fullarticle/2844116?guestAccessKey=0d7f20b5-a2e0-48c8-94c9-cee3a1efb051&utm_medium=email&utm_source=postup_jn&utm_campaign=article_alert-jama&utm_content=etoc-tfl_&utm_term=032426
cbarbermd
npub17a…8ydzp
2026-03-24 20:39:03 UTC
Author Public Key
npub17aet92c7rt96vy82n33kckddwulf6ecygejwgu8669kj7367zg9sw8ydzpSeen on
wss://relay.ditto.pubPublished at
2026-03-24 20:39:03 UTCEvent JSON
{
"id": "6c3bdb8eb8b6865b7583226feb6dc0a72c3a7bfceb5a17cdbab3e0f3cc541b9d",
"pubkey": "f772b2ab1e1acba610ea9c636c59ad773e9d67044664e470fad16d2f475e120b",
"created_at": 1774384743,
"kind": 1,
"tags": [
[
"t",
"press"
],
[
"t",
"evidencebased"
],
[
"proxy",
"https://med-mastodon.com/users/cbarbermd/statuses/116286078571302106",
"activitypub"
],
[
"client",
"Mostr",
"31990:6be38f8c63df7dbf84db7ec4a6e6fbbd8d19dca3b980efad18585c46f04b26f9:mostr",
"wss://relay.ditto.pub"
]
],
"content": "NEW: Have acute appendicitis? To the OR… not so fast.\n\n10-year RCT data (APPAC) show antibiotics alone work for many with uncomplicated disease:\n• ~56% avoided surgery\n• Recurrence ~38%\n• MUCH fewer complications (8.5% vs 27.4% with surgery)\n\nAppendectomy isn’t the only answer anymore. #press #EvidenceBased #evidencebased #press https://jamanetwork.com/journals/jama/fullarticle/2844116?guestAccessKey=0d7f20b5-a2e0-48c8-94c9-cee3a1efb051\u0026utm_medium=email\u0026utm_source=postup_jn\u0026utm_campaign=article_alert-jama\u0026utm_content=etoc-tfl_\u0026utm_term=032426",
"sig": "c504613ff93443956e54603c5ba12d7eb9bd7a1ddf40ee9c07a94e22693c18812e017a55d610aed198f14cd31e499952b97ca5bd14b6da29ff87a994494e6fce"
}