When I moved into software dev environment, I worked on public transport projects. The most boring part - showing users how to get from point A to point B. Guess what? That had an impact on health and safety. Person misses their train/tram/bus to the Dr appointment and can't reschedule - doesn't get their medication filled for a few weeks. Person chooses driving over using PT. Someone might miss their appointment to get a job or visit centerlink/servicesaustralia.
I worked on many government related websites. I'm only a single cog in the system, so you can't blame me for all the terrible gov websites. But I always tried to focus on "if this breaks, it could cause someone a mental breakdown". I'm not sure how many people have had this. I've had it just ordering pizza. That final last straw.