Nature (RSS/Atom feed) on Nostr: Structural energetics of cold sensitivity Nature, Published online: 25 March 2026; ...

Structural energetics of cold sensitivity

Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10276-2][1]

Data from cryogenic electron microscopy combined with hydrogen–deuterium exchange mass spectrometry inform a mechanism for cold-evoked activation of the TRPM8 channel, providing a structural and energetic framework to explain cold sensitivity.

[1]: https://www.nature.com/articles/s41586-026-10276-2


https://www.nature.com/articles/s41586-026-10276-2