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2024-11-04 18:19:08 UTC

Spencer LaVere Smith on Nostr: Big paper from the International Brain Lab group: One takeaway is that using ...

Big paper from the International Brain Lab group: https://elifesciences.org/reviewed-preprints/100840 One takeaway is that using stereotaxic coordinates involves variance which "... is sizeable enough to impact probe targeting to desired brain regions and poses a limit on the resolution of probe targeting." Lots of labs do posthoc histology verification, which can help.

Functional targeting is my favorite. Here's a figure from the supplement to one of our preprints. Functional targeting is way better than using skull landmarks. https://www.biorxiv.org/content/10.1101/2023.08.27.555017v1