MCDuncanLab on Nostr: For example, last week we had a somewhat complex paper that examined the roles of ...

For example, last week we had a somewhat complex paper that examined the roles of sorting signals and transmembrane domains in ER and Golgi exit.

The main conclusion was that sorting signals are the main driver of ER exit, and transmembrane domain affinity for ordered domains is the main driver of rapid Golgi exit. There is a minor contribution of ordered domain affinity for the ER exit.