bryan on Nostr: There is an enzyme in adipose tissue called aromatase. This enzyme converts ...
There is an enzyme in adipose tissue called aromatase.
This enzyme converts testosterone to estrogen.
Converting fat (adipose) tissue to muscle will raise T because less will be converted to estradiol [other reasons as well].
Many times, in obese patients, if you start TRT and the levels do not rise, it’s because it’s all being converted to estrogen.
You can use an aromatase inhibitor such as anastrazole to prevent this, but it’s best just to lose the weight (do your part!).
I don’t like using enzyme blockers because you are tinkering with a complex biological system and risks start to go up.
Giving T, the end product, for the right patient can contribute to improved health.
Published at
2024-08-27 13:22:43Event JSON
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"content": "There is an enzyme in adipose tissue called aromatase.\n\nThis enzyme converts testosterone to estrogen.\n\nConverting fat (adipose) tissue to muscle will raise T because less will be converted to estradiol [other reasons as well].\n\nMany times, in obese patients, if you start TRT and the levels do not rise, it’s because it’s all being converted to estrogen.\n\nYou can use an aromatase inhibitor such as anastrazole to prevent this, but it’s best just to lose the weight (do your part!).\n\nI don’t like using enzyme blockers because you are tinkering with a complex biological system and risks start to go up.\n\nGiving T, the end product, for the right patient can contribute to improved health.",
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