Structural basis of supercoiling-induced CRISPR–Cas9 off-target activity
Nature, Published online: 25 March 2026; [doi:10.1038/s41586-026-10255-7][1]
Cas9 structures explain topology sensing and off-target activation.
[1]: https://www.nature.com/articles/s41586-026-10255-7
https://www.nature.com/articles/s41586-026-10255-7
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2026-03-25 17:08:52 UTC
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