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  <updated>2026-05-12T12:53:17Z</updated>
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  <title>Nostr notes by Mike Malaska</title>
  <author>
    <name>Mike Malaska</name>
  </author>
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  <entry>
    <id>https://yabu.me/nevent1qqsvc0axenwr6rn9h0gyyarwx9nzp0vdeawaey3w0p6e3tzhvfxy78gzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xn5myf4</id>
    
      <title type="html">Poll time! Here is a quote from NASA Administrator Jared Isaacman ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsvc0axenwr6rn9h0gyyarwx9nzp0vdeawaey3w0p6e3tzhvfxy78gzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xn5myf4" />
    <content type="html">
      Poll time! &lt;br/&gt;&lt;br/&gt;Here is a quote from NASA Administrator Jared Isaacman (see: &lt;a href=&#34;https://deepspace.social/@mike_malaska/116384128140587012&#34;&gt;https://deepspace.social/@mike_malaska/116384128140587012&lt;/a&gt;):&lt;br/&gt;&lt;br/&gt;“If we wake up and we see our rival’s taikonauts on the moon before we’re able to return, the blow to American exceptionalism will be so damaging, the shock wave will be felt around the world.”&lt;br/&gt;&lt;br/&gt;If China beat the US to the Moon, how would you feel personally?
    </content>
    <updated>2026-04-11T20:25:32Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqs8scy2h77sekvz9jyy5s4fsd3865gmdzxyef904d6k8sexs3u7vqgzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xpjxnlw</id>
    
      <title type="html">Came across this wide-view shot of flooded Badwater Basin in ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqs8scy2h77sekvz9jyy5s4fsd3865gmdzxyef904d6k8sexs3u7vqgzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xpjxnlw" />
    <content type="html">
      Came across this wide-view shot of flooded Badwater Basin in Death Valley National Park from March 2024. Click to embiggen and see the full view.&lt;br/&gt; &lt;img src=&#34;https://cdn.masto.host/deepspacesocial/media_attachments/files/116/224/929/277/619/711/original/2e4d05b5ae87f7a0.jpg&#34;&gt; &lt;br/&gt;
    </content>
    <updated>2026-03-14T01:31:33Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsgp6zd3ml44jf49nj9sza0zyqqhr7as4hnzgkwphwssv645v2y6zczyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x7vdfpu</id>
    
      <title type="html">ahhh! Got some lit! ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsgp6zd3ml44jf49nj9sza0zyqqhr7as4hnzgkwphwssv645v2y6zczyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x7vdfpu" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqsrzsa5m08545hlv9xl5pg4jje6myjeh9svx6fzrncexj2z7z370lcshvzdv&#39;&gt;nevent1q…vzdv&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;ahhh! Got some lit!&lt;br/&gt;&lt;br/&gt;&lt;a href=&#34;https://www.sciencedirect.com/science/article/abs/pii/S0019103510004641&#34;&gt;https://www.sciencedirect.com/science/article/abs/pii/S0019103510004641&lt;/a&gt;&lt;br/&gt;&lt;br/&gt;This is a pay-for article, but it seems that CO2 not happy on Iapetus. Won&amp;#39;t trap for long.&lt;br/&gt;&lt;br/&gt;What CO2 there is seems associated with low albedo stuff. (Not where youd expect from cold trapping)&lt;br/&gt;&lt;br/&gt;So CO2 is either being generated from UV action of exposed organics/ice (in dark lag&#43;UV produced superoxides from ice photolysis) or possibly-maybe CO2 got trapped up by associations. mineral/carbon stuff in dark lag material.
    </content>
    <updated>2026-02-19T19:13:35Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqs9xf0cahh3qkajvphs0wpxlnfl39prryy2etv7pehds2mp4atlysgzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x05nsfl</id>
    
      <title type="html">(I think the volatile moving around on Iapetus is still H2O, CO2 ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqs9xf0cahh3qkajvphs0wpxlnfl39prryy2etv7pehds2mp4atlysgzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x05nsfl" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqsrxfjawvflvysjw3r8snkwpyqpcrhwt6v29nghkmmutlt9xafd6vq9unlkf&#39;&gt;nevent1q…nlkf&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;(I think the volatile moving around on Iapetus is still H2O, CO2 is trapped pretty everywhere, but slightly more in dark lag stuff.)
    </content>
    <updated>2026-02-19T18:38:10Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsdnnfgsswu2qzzr244jt3thgjdguuhzhqetke96w5n8s0wn8uk7kqzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xlwmqcy</id>
    
      <title type="html">Like Iapetus, but free.</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsdnnfgsswu2qzzr244jt3thgjdguuhzhqetke96w5n8s0wn8uk7kqzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xlwmqcy" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqsyq4dut58ql8uzpyeygd4u9s0huv6wd24wyjkdn0sfvr3pzxhl77q35l66n&#39;&gt;nevent1q…l66n&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;Like Iapetus, but free.
    </content>
    <updated>2026-02-19T18:31:09Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsw4f9rjgyudjurtrkvc284hvl4y6c25n08tcqr4ll5t00hsyjycygzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xh73pct</id>
    
      <title type="html">View from spheroidally weathered granite blocks in the Alabama ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsw4f9rjgyudjurtrkvc284hvl4y6c25n08tcqr4ll5t00hsyjycygzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xh73pct" />
    <content type="html">
      View from spheroidally weathered granite blocks in the Alabama Hills National Scenic Area, California.&lt;br/&gt; &lt;img src=&#34;https://cdn.masto.host/deepspacesocial/media_attachments/files/116/054/671/339/593/479/original/d1259023d888b068.jpg&#34;&gt; &lt;br/&gt;
    </content>
    <updated>2026-02-11T23:51:47Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqs8vcl685442ep64ts43c37vhvxvkugalrzjlwa5dfvzuats4aynlczyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xe5s9xj</id>
    
      <title type="html">&amp;#34;Gosh, Mike, I bet running around in the desert you probably ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqs8vcl685442ep64ts43c37vhvxvkugalrzjlwa5dfvzuats4aynlczyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xe5s9xj" />
    <content type="html">
      &amp;#34;Gosh, Mike, I bet running around in the desert you probably see a lot of wierd-looking plants, right?&amp;#34;&lt;br/&gt;&lt;br/&gt;Oh yeah.&lt;br/&gt;&lt;br/&gt;I present to you the Pagoda Buckwheat.&lt;br/&gt;&lt;br/&gt;This stands only about 20 cm high.&lt;br/&gt;&lt;br/&gt;It is very common along the roadside dropping into and climbing out of Panamint Valley on the road to Death Valley from Olancha, California.&lt;br/&gt; &lt;img src=&#34;https://cdn.masto.host/deepspacesocial/media_attachments/files/116/047/425/244/997/761/original/9835f9bf1ad0cfa9.jpg&#34;&gt; &lt;br/&gt;
    </content>
    <updated>2026-02-10T17:09:43Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqs9ycmpz94y40460gzrh7239mjcf2vu33e3ka07nk9qhhwwezg0kqszyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xmcrtcu</id>
    
      <title type="html">Fine. I&amp;#39;ll ditch the hashtag.</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqs9ycmpz94y40460gzrh7239mjcf2vu33e3ka07nk9qhhwwezg0kqszyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xmcrtcu" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqs8aex2l3q8vwe2shjcyqlff3hwzepy7jkl48ltwx6hp4p25sxywxcrlxls2&#39;&gt;nevent1q…xls2&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;Fine. I&amp;#39;ll ditch the hashtag.
    </content>
    <updated>2026-02-02T05:30:48Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqst72w79vlu9avttvf4khkxxm98t7tn3t055m49j7gnx4k87ksc4sszyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x7qqct3</id>
    
      <title type="html">Seriously? I can&amp;#39;t post explanations?</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqst72w79vlu9avttvf4khkxxm98t7tn3t055m49j7gnx4k87ksc4sszyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x7qqct3" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqsr5vx6xh9d7pamgat4wtkw2eake7fldsvu9vpvtls08uzpt5xpzfqxgzs08&#39;&gt;nevent1q…zs08&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;Seriously? I can&amp;#39;t post explanations?
    </content>
    <updated>2026-02-02T00:49:03Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqs0neg9qmqt9s5cl2svdh4cpfgaeq26t5aj5w99x67dw6gfpdudntgzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xvu54q5</id>
    
      <title type="html">The edge of a canebrake in snowy woods. Orange County, North ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqs0neg9qmqt9s5cl2svdh4cpfgaeq26t5aj5w99x67dw6gfpdudntgzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xvu54q5" />
    <content type="html">
      The edge of a canebrake in snowy woods. Orange County, North Carolina.&lt;br/&gt;&lt;br/&gt;#SilentSunday&lt;br/&gt;&lt;br/&gt;(Wkipedia entry on Canebreaks. A moist lowland native bamboo thicket common in SE of North America: &lt;a href=&#34;https://en.wikipedia.org/wiki/Canebrake&#34;&gt;https://en.wikipedia.org/wiki/Canebrake&lt;/a&gt;)&lt;br/&gt; &lt;img src=&#34;https://cdn.masto.host/deepspacesocial/media_attachments/files/115/997/475/282/716/510/original/9269f45e560227eb.jpg&#34;&gt; &lt;br/&gt;
    </content>
    <updated>2026-02-01T21:27:05Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsfwefm6mfmjlnty6208qwuf5cw006sthfed2j5h4klhkteuuzpdjqzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xg96xj4</id>
    
      <title type="html">Part 2: Tryptophan discovery: How do we know what we know? As ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsfwefm6mfmjlnty6208qwuf5cw006sthfed2j5h4klhkteuuzpdjqzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xg96xj4" />
    <content type="html">
      Part 2: Tryptophan discovery: How do we know what we know?&lt;br/&gt;&lt;br/&gt;As promised, we gonna circle back on that tryptophan discovery.&lt;br/&gt;(For Part 1 in this series see here: &lt;a href=&#34;https://deepspace.social/@mike_malaska/115653001232082594&#34;&gt;https://deepspace.social/@mike_malaska/115653001232082594&lt;/a&gt;)&lt;br/&gt;&lt;br/&gt;And this gets to an even bigger question in #astrobiology (and life in general):&lt;br/&gt;“How do you know what you know?”&lt;br/&gt;&lt;br/&gt;We gonna dive deep into the analytical chemistry of that reported tryptophan detection, digging into the supplementary information analysis.&lt;br/&gt;&lt;br/&gt;[thread]&lt;blockquote class=&#34;border-l-05rem border-l-strongpink border-solid&#34;&gt;&lt;div class=&#34;-ml-4 bg-gradient-to-r from-gray-100 dark:from-zinc-800 to-transparent mr-0 mt-0 mb-4 pl-4 pr-2 py-2&#34;&gt;quoting &lt;br/&gt;&lt;span itemprop=&#34;mentions&#34; itemscope itemtype=&#34;https://schema.org/Article&#34;&gt;&lt;a itemprop=&#34;url&#34; href=&#34;/note1nz47j0las3gwyqd4n62kp2l0dst688zmyc6dn045e8lr3vs0207s2tzjmv&#34; class=&#34;bg-lavender dark:prose:text-neutral-50 dark:text-neutral-50 dark:bg-garnet px-1&#34;&gt;note1nz4…zjmv&lt;/a&gt;&lt;/span&gt;&lt;br/&gt; &lt;/div&gt; Why is the potential discovery of tryptophan in an asteroid sample such a big deal for #astrobiology?&lt;br/&gt;&lt;br/&gt;Gonna do a deep dive behind the headlines.&lt;br/&gt;&lt;br/&gt;For starters, here is a link to the discovery article: &lt;a href=&#34;https://www.pnas.org/doi/10.1073/pnas.2512461122&#34;&gt;https://www.pnas.org/doi/10.1073/pnas.2512461122&lt;/a&gt;&lt;br/&gt;&lt;br/&gt;thread time! &lt;/blockquote&gt;
    </content>
    <updated>2025-12-12T21:23:15Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsf32lf8l7cg58zqx6ea9tq40hkc9arn3djvdxeh66vnl3ckg848lgzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xx3uw2l</id>
    
      <title type="html">Why is the potential discovery of tryptophan in an asteroid ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsf32lf8l7cg58zqx6ea9tq40hkc9arn3djvdxeh66vnl3ckg848lgzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xx3uw2l" />
    <content type="html">
      Why is the potential discovery of tryptophan in an asteroid sample such a big deal for #astrobiology?&lt;br/&gt;&lt;br/&gt;Gonna do a deep dive behind the headlines.&lt;br/&gt;&lt;br/&gt;For starters, here is a link to the discovery article: &lt;a href=&#34;https://www.pnas.org/doi/10.1073/pnas.2512461122&#34;&gt;https://www.pnas.org/doi/10.1073/pnas.2512461122&lt;/a&gt;&lt;br/&gt;&lt;br/&gt;thread time!
    </content>
    <updated>2025-12-03T01:19:10Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsvgymy9gmsdc69cw5r96rrsppdrhsnh038fmezwfdegxny2dpqssszyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xrt2pd5</id>
    
      <title type="html">Freeze expected tomorrow. I pulled the okra and put it by compost ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsvgymy9gmsdc69cw5r96rrsppdrhsnh038fmezwfdegxny2dpqssszyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xrt2pd5" />
    <content type="html">
      Freeze expected tomorrow. I pulled the okra and put it by compost bin to chop later.&lt;br/&gt;&lt;br/&gt;Despite being late season, yanled out of the ground, and thrown in a pile awaiting a killing freeze, it is still trying!&lt;br/&gt;&lt;br/&gt;That&amp;#39;s the spirit!&lt;br/&gt;&lt;br/&gt;Be like the okra.&lt;br/&gt; &lt;img src=&#34;https://cdn.masto.host/deepspacesocial/media_attachments/files/115/521/233/918/285/085/original/766601edb9e47974.jpg&#34;&gt; &lt;br/&gt;
    </content>
    <updated>2025-11-09T18:53:30Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsqt9jx8jv2dr78rxgadap5h673xfvelat9kxf6dycpwf9agqtxqwgzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xys9s5q</id>
    
      <title type="html">My Incedible Superpower is spotting useful seedlings at the three ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsqt9jx8jv2dr78rxgadap5h673xfvelat9kxf6dycpwf9agqtxqwgzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xys9s5q" />
    <content type="html">
      My Incedible Superpower is spotting useful seedlings at the three or four-leaf stage.&lt;br/&gt;&lt;br/&gt;I&amp;#39;m a lazy gardner. I just let open pollinated stuff go to seed, sprout wherever, then spot and carefully transplant later.&lt;br/&gt;&lt;br/&gt;Here is an example bed I let idle. Over a year ago I had lettuce in here. There are a bunch of weeds, but one little lettuce seedling.&lt;br/&gt;&lt;br/&gt;Can you find it?&lt;br/&gt;&lt;br/&gt;#gardening&lt;br/&gt; &lt;img src=&#34;https://cdn.masto.host/deepspacesocial/media_attachments/files/115/481/715/186/009/092/original/43eac647efe8f224.jpg&#34;&gt; &lt;br/&gt;
    </content>
    <updated>2025-11-02T19:24:27Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqs8nfhuqenz96vre2ddchjfek2na7qga5d46g9nr3gpyss84cxqkmszyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x3zj3ag</id>
    
      <title type="html">Please RT. This link will help find the nearest foodbank in the ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqs8nfhuqenz96vre2ddchjfek2na7qga5d46g9nr3gpyss84cxqkmszyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x3zj3ag" />
    <content type="html">
      Please RT. This link will help find the nearest foodbank in the United States. There is a search bar by zip code that provides a list of food pantries nearby.&lt;br/&gt;&lt;br/&gt;&lt;a href=&#34;https://www.feedingamerica.org/find-your-local-foodbank&#34;&gt;https://www.feedingamerica.org/find-your-local-foodbank&lt;/a&gt;
    </content>
    <updated>2025-10-29T23:07:18Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqs0lp5gjm2hzvdzly3gad0rcnhpwxz5gs48wlelwe72ezwhlvchxeszyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xn0qcey</id>
    
      <title type="html">By combining gases, adding some metal vapor, and using colored ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqs0lp5gjm2hzvdzly3gad0rcnhpwxz5gs48wlelwe72ezwhlvchxeszyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xn0qcey" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqsve0gy352r7uvnsgqaluapvskhnvyt3awkw82wjl74rv00a0hfn8cwc3xa2&#39;&gt;nevent1q…3xa2&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;By combining gases, adding some metal vapor, and using colored glass and blowing multiple tubes with different effects you can make some interesting signs.&lt;br/&gt;&lt;br/&gt;Like the neon sign for Dr. Kilzum pest control services. A lot of different colors and shapes on this 10 foot tall sign. Imagine blowing all those glass tubes!&lt;br/&gt; &lt;img src=&#34;https://cdn.masto.host/deepspacesocial/media_attachments/files/115/274/209/558/995/744/original/e7295e4bab25cd90.jpg&#34;&gt; &lt;br/&gt;
    </content>
    <updated>2025-09-27T03:52:00Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsve0gy352r7uvnsgqaluapvskhnvyt3awkw82wjl74rv00a0hfn8czyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x9lk307</id>
    
      <title type="html">&amp;#34;Neon&amp;#34; is a generic term for sticking rarified noble ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsve0gy352r7uvnsgqaluapvskhnvyt3awkw82wjl74rv00a0hfn8czyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x9lk307" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqsxhcvpmegzlkwh04adfw63cpx38zrhakxy0z8vwkgq4nnf9s7up7sgzm87z&#39;&gt;nevent1q…m87z&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;&amp;#34;Neon&amp;#34; is a generic term for sticking rarified noble gases (and maybe some metal vapor) in a tube and zapping it with high voltage alternating current.&lt;br/&gt;&lt;br/&gt;The high voltage strips off the outermost electron, and when it pops back in, it releases a photon at the corresponding quantum level.&lt;br/&gt;&lt;br/&gt;You get the same effect in an aurora. But noble gases are not corrosive.&lt;br/&gt;&lt;br/&gt;Here is a transparent display that show the different noble gases.&lt;br/&gt; &lt;img src=&#34;https://cdn.masto.host/deepspacesocial/media_attachments/files/115/274/139/882/913/811/original/c4a7633f5e15fff0.jpg&#34;&gt; &lt;br/&gt;
    </content>
    <updated>2025-09-27T03:33:17Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsxhcvpmegzlkwh04adfw63cpx38zrhakxy0z8vwkgq4nnf9s7up7szyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xeu3rj5</id>
    
      <title type="html">Yes. That previous piece is a neon art representation of the ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsxhcvpmegzlkwh04adfw63cpx38zrhakxy0z8vwkgq4nnf9s7up7szyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xeu3rj5" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqs9nl3f84cz6rzw26wfgfn9tu76kpq3s04v2lpryjyka7wjfcwsclceg0efv&#39;&gt;nevent1q…0efv&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;Yes. That previous piece is a neon art representation of the freeway system around downtown Los Angeles!&lt;br/&gt;&lt;br/&gt;Here is another very abstract large piece that was next to the LA nein piece. It was pretty big, maybe 2m on a side.&lt;br/&gt; &lt;img src=&#34;https://cdn.masto.host/deepspacesocial/media_attachments/files/115/274/108/152/167/988/original/71b37b89e9f184c8.jpg&#34;&gt; &lt;br/&gt;
    </content>
    <updated>2025-09-27T03:24:19Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqs9nl3f84cz6rzw26wfgfn9tu76kpq3s04v2lpryjyka7wjfcwsclczyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xwf6d6z</id>
    
      <title type="html">Today I went to the Neon Museum of Modern Art in Glendale, CA. ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqs9nl3f84cz6rzw26wfgfn9tu76kpq3s04v2lpryjyka7wjfcwsclczyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xwf6d6z" />
    <content type="html">
      Today I went to the Neon Museum of Modern Art in Glendale, CA. Very fun!&lt;br/&gt;&lt;br/&gt;Small, niche, and kitsch.&lt;br/&gt;&lt;br/&gt;They had lots of neat glowy stuff. I took many pix. For the ones that flash, I&amp;#39;ll post a CW.&lt;br/&gt;&lt;br/&gt;The museum also has a workshop and for bigger bucks you can take a class to learn how to be a &amp;#34;neon bender&amp;#34;.&lt;br/&gt;&lt;br/&gt;(Anyone want to guess what this abstract neon piece represents? Answer in next post.)&lt;br/&gt;&lt;br/&gt;[Thread]&lt;br/&gt; &lt;img src=&#34;https://cdn.masto.host/deepspacesocial/media_attachments/files/115/274/073/515/159/732/original/9e34b7de95b8f041.jpg&#34;&gt; &lt;br/&gt;
    </content>
    <updated>2025-09-27T03:15:59Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsfpsg6zl8xr5ls020gqurtwhrj3kezs3pnpthnpe422c0qkgm74jqzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xfyz236</id>
    
      <title type="html">The NISAR mission&amp;#39;s radar antenna has fully unfurled! ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsfpsg6zl8xr5ls020gqurtwhrj3kezs3pnpthnpe422c0qkgm74jqzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xfyz236" />
    <content type="html">
      The NISAR mission&amp;#39;s radar antenna has fully unfurled! Whoo-hoo!&lt;br/&gt;&lt;br/&gt;&lt;a href=&#34;https://www.jpl.nasa.gov/news/giant-radar-antenna-reflector-on-nasa-isro-satellite-in-full-bloom/&#34;&gt;https://www.jpl.nasa.gov/news/giant-radar-antenna-reflector-on-nasa-isro-satellite-in-full-bloom/&lt;/a&gt;
    </content>
    <updated>2025-08-16T00:33:18Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsd0a3fuz2jpy04k28v477snuglwsvc00qct38xw5w7kqukfndjvfqzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x0aa9l6</id>
    
      <title type="html">Sunset on the Salish Sea. Lighthouse in Mukilteo, Washinton at ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsd0a3fuz2jpy04k28v477snuglwsvc00qct38xw5w7kqukfndjvfqzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x0aa9l6" />
    <content type="html">
      Sunset on the Salish Sea.&lt;br/&gt;&lt;br/&gt;Lighthouse in Mukilteo, Washinton at sunset.&lt;br/&gt; &lt;img src=&#34;https://cdn.masto.host/deepspacesocial/media_attachments/files/114/895/364/010/273/281/original/8e1c5c723f90079b.jpg&#34;&gt; &lt;br/&gt;
    </content>
    <updated>2025-07-22T06:06:03Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsxnhe85lurw0849fqcjw6a3txp9yksz6wluqpd2rjjsadfg2wndtszyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xejf9n5</id>
    
      <title type="html">Floating in Kraken Mare and looking for life has its own issues. ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsxnhe85lurw0849fqcjw6a3txp9yksz6wluqpd2rjjsadfg2wndtszyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xejf9n5" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqst2k02nnw684nlfau2v2x57uk45tpnddrzjdcp0p4rg87r2dkt6tq0lx3sx&#39;&gt;nevent1q…x3sx&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;Floating in Kraken Mare and looking for life has its own issues.&lt;br/&gt;&lt;br/&gt;What would you look for? You&amp;#39;d filter out any solids prior to analyzing the liquid so you dont gunk stuff up. Back to only looking at a handful of soluble molecules (srsly. I prepared this list for the Oceanus Calypso probe. These are not exciting molecules.)&lt;br/&gt;&lt;br/&gt;At low T, you&amp;#39;d  want to look for molecular associations. Need in situ NMR, not destructive GC.&lt;br/&gt;&lt;br/&gt;I&amp;#39;m a very wet blanket regarding  methane-based life.
    </content>
    <updated>2025-04-26T15:47:01Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqs8pp4sn9han9ywrqaaqnwse0epxazw0lryzdzyqzveefvjy059nlczyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xhf6kve</id>
    
      <title type="html">Imma push back on this way hard. Cryogenic methane is a truly ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqs8pp4sn9han9ywrqaaqnwse0epxazw0lryzdzyqzveefvjy059nlczyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xhf6kve" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqsrxa6ee8jrxq2rxayxghsjdg4pgeaq9rfad8z7mqedrwnav56el5gs6qu53&#39;&gt;nevent1q…qu53&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;Imma push back on this way hard.&lt;br/&gt;&lt;br/&gt;Cryogenic methane is a truly lousy solvent. There is a VERY short list of organic molecules that will dissolve in it and let you shuttle energy-carrying molecules from one place to another.&lt;br/&gt;&lt;br/&gt;I challenge anyone to build up a biochemical cascade using ONLY cyclopropane and butane.&lt;br/&gt;&lt;br/&gt;(And I&amp;#39;m not even mentioning synthesis of A&#43;B--&amp;gt;AB where AB is so insoluble it gloms itself to the enzyme active site - catalytic turnover of one.)
    </content>
    <updated>2025-04-26T15:26:42Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqs0crk5ux3e64w8xn8hgyk32ue239kpm7q35zxzp37wvrrggj0w0zszyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x2dhzww</id>
    
      <title type="html">The other recurring theme is that we need to improve planetary ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqs0crk5ux3e64w8xn8hgyk32ue239kpm7q35zxzp37wvrrggj0w0zszyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x2dhzww" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqsgcma9h8j5e36xqt43gpnj54g2fpddakx87pc970km3zyusahkgggkds7cj&#39;&gt;nevent1q…s7cj&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;The other recurring theme is that we need to improve planetary instrumentation and lower the detection limit. &lt;br/&gt;&lt;br/&gt;1E3 cells per cm3 is just not good enough. We need to push to much lower. &lt;br/&gt;&lt;br/&gt;This will also help us explore Earth and can also help with medical technologies (just how &amp;#34;sterile&amp;#34; is that water, anyway?)&lt;br/&gt;&lt;br/&gt;So this article also serves as a call for better instrumentation for planetary #astrobiology.  &lt;br/&gt;&lt;br/&gt;There will be more on that in a few weeks. (Stay tuned)&lt;br/&gt;&lt;br/&gt;\end thread.
    </content>
    <updated>2025-04-26T13:56:48Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsgcma9h8j5e36xqt43gpnj54g2fpddakx87pc970km3zyusahkgggzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xcrrzan</id>
    
      <title type="html">But the really big news (that got missed in the hype) is that ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsgcma9h8j5e36xqt43gpnj54g2fpddakx87pc970km3zyusahkgggzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xcrrzan" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqs25tvje5l9l9x99cxxv0xl5e2w2h7cp3jdzun5lpm68dcggwg0dtczv302p&#39;&gt;nevent1q…302p&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;But the really big news (that got missed in the hype) is that TITAN IS HABITABLE.&lt;br/&gt;&lt;br/&gt;Our numbers show that it could support at least a small dog worth of biomass. &lt;br/&gt;&lt;br/&gt;(If you found a small dog on Titan you&amp;#39;d be pretty happy, right?)&lt;br/&gt;&lt;br/&gt;So the numbers, while low, will likely only go up as we get better data (more metabolisms) and better ideas of where to look.
    </content>
    <updated>2025-04-26T13:53:38Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqs25tvje5l9l9x99cxxv0xl5e2w2h7cp3jdzun5lpm68dcggwg0dtczyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xhthflz</id>
    
      <title type="html">In micropockets, you can get concentration effects of about 1E6 ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqs25tvje5l9l9x99cxxv0xl5e2w2h7cp3jdzun5lpm68dcggwg0dtczyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xhthflz" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqszcue3uy8yzqy3afvyjcdyu8lenr08k966fhpy7g9vv0qa2cu7qncx74llz&#39;&gt;nevent1q…4llz&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;In micropockets, you can get concentration effects of about 1E6 as ice grains squeeze out non-water molecules. So you could get a hyperlocalized concentration. &lt;br/&gt;&lt;br/&gt;Which could push an effective cell count to 1E3 cells per cm3 which is now in range of current state-of-the art instrumentation.&lt;br/&gt;&lt;br/&gt;There are other ways to localize biomass too. Happens all the time here on Earth.
    </content>
    <updated>2025-04-26T13:50:34Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqszcue3uy8yzqy3afvyjcdyu8lenr08k966fhpy7g9vv0qa2cu7qnczyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xzwcs07</id>
    
      <title type="html">Another thing is where are all those cells. Are they gonna be ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqszcue3uy8yzqy3afvyjcdyu8lenr08k966fhpy7g9vv0qa2cu7qnczyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xzwcs07" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqsvv48z4muk49cr349jxwzehtrctqhlec7rhwmqvvxh0l75780dc6qy27u4l&#39;&gt;nevent1q…7u4l&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;Another thing is where are all those cells. Are they gonna be swimming around in the dilute-ass ocean?&lt;br/&gt;&lt;br/&gt;(Y&amp;#39;all should know I think the ocean of ocean worlds is the WORST place to look for life. Big. Dilute. Boring.)&lt;br/&gt;&lt;br/&gt;Life loves interfaces.  Ice-ocean interface, ice-bottom interface, brinicles, cold-seeps (up or down), and especially micropockets in ice.&lt;br/&gt;&lt;br/&gt;(I&amp;#39;ll be posting something exciting about micropockets in a few weeks. Stay tuned.)
    </content>
    <updated>2025-04-26T13:46:38Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsvv48z4muk49cr349jxwzehtrctqhlec7rhwmqvvxh0l75780dc6qzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xanr9rs</id>
    
      <title type="html">An analogy is that 1 person can live on 1 frozen pizza a day. So ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsvv48z4muk49cr349jxwzehtrctqhlec7rhwmqvvxh0l75780dc6qzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xanr9rs" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqsr0r6craaeq6welwjlfe8a24qcxmvws57wzc8pet4w98wqmhv2ntcw8r2cp&#39;&gt;nevent1q…r2cp&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;An analogy is that 1 person can live on 1 frozen pizza a day.  So if you go into a grocery store and just count number of frozen pizzas, then that gives you an estimate of how many people that grocery store can feed, right?&lt;br/&gt;&lt;br/&gt;(Wrong. there are also frozen Turkey Pot Pies. Maybe other things, too. :) )
    </content>
    <updated>2025-04-26T13:42:28Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsr0r6craaeq6welwjlfe8a24qcxmvws57wzc8pet4w98wqmhv2ntczyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xfrjkcl</id>
    
      <title type="html">We only considered glycine fermentation. There are lots of other ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsr0r6craaeq6welwjlfe8a24qcxmvws57wzc8pet4w98wqmhv2ntczyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xfrjkcl" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqs8crxqdahwvqrgx2k46p5efppqmn3eeagzc2fsxaswy3m8xth5llswfde7s&#39;&gt;nevent1q…de7s&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;We only considered glycine fermentation. &lt;br/&gt;&lt;br/&gt;There are lots of other molecules that could be yummy microbe food (naphthalene is my favorite).  But we only had really really good numbers for terrestrial microbes for glycine at low temperatures and high pressures. So that&amp;#39;s a data issue. &lt;br/&gt;&lt;br/&gt;(The article is a call-out for low T, high P, microbiology experiments for funky metabolisms).
    </content>
    <updated>2025-04-26T13:39:18Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqs8crxqdahwvqrgx2k46p5efppqmn3eeagzc2fsxaswy3m8xth5llszyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xfgvkn2</id>
    
      <title type="html">If you dilute that out over the whole subsurface ocean, it give ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqs8crxqdahwvqrgx2k46p5efppqmn3eeagzc2fsxaswy3m8xth5llszyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xfgvkn2" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqs92hnmc9zrs55wqk6ja7z6cngc0u9fhw6vhlg70ts0gguwkz752rce6xt69&#39;&gt;nevent1q…xt69&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;If you dilute that out over the whole subsurface ocean, it give you numbers around 0.001 cells per cm3 (1E-3 cells per cm3) - that is one hundred time LOWER than medically sterile.&lt;br/&gt;&lt;br/&gt;That&amp;#39;s bad news for Titan #astrobiology  right?&lt;br/&gt;&lt;br/&gt;Well, not really.&lt;br/&gt;&lt;br/&gt;Here&amp;#39;s why:
    </content>
    <updated>2025-04-26T13:36:21Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqs92hnmc9zrs55wqk6ja7z6cngc0u9fhw6vhlg70ts0gguwkz752rczyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xqq5yxl</id>
    
      <title type="html">In the Titan habitability calculation, we estimated the total ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqs92hnmc9zrs55wqk6ja7z6cngc0u9fhw6vhlg70ts0gguwkz752rczyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xqq5yxl" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqsx393m8ywcj5kywyd6g0fc75cvhmq9dulvkf423lupwctghyr9enq6726l3&#39;&gt;nevent1q…26l3&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;In the Titan habitability calculation, we estimated the total amount of cell mass that could be supported by glycine fermentation based on the estimate glycine delivery from the top surface all the way through 100 km of ice into the deep subsurface ocean of Titan.&lt;br/&gt;&lt;br/&gt;And we came up with a small dog&amp;#39;s worth of cell mass.&lt;br/&gt;&lt;br/&gt;Affholder et al. 2025 (open-access article): &lt;a href=&#34;https://iopscience.iop.org/article/10.3847/PSJ/adbc66&#34;&gt;https://iopscience.iop.org/article/10.3847/PSJ/adbc66&lt;/a&gt;
    </content>
    <updated>2025-04-26T13:32:53Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsx393m8ywcj5kywyd6g0fc75cvhmq9dulvkf423lupwctghyr9enqzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xyuwrp2</id>
    
      <title type="html">Here are some numbers for comparison, in microbes per cm3 volume: ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsx393m8ywcj5kywyd6g0fc75cvhmq9dulvkf423lupwctghyr9enqzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xyuwrp2" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqs28ndv9pgv0a8t0fkqtl7fmv97pef4nfespzp4s7tp4u9r8dnwqgg0kl7qf&#39;&gt;nevent1q…l7qf&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;Here are some numbers for comparison, in microbes per cm3 volume:&lt;br/&gt;&lt;br/&gt;Theoretical maximum limit: 1E15 cells per cm3&lt;br/&gt;{this is based on the theoretical lower limit for microbial cells}&lt;br/&gt;Human body: about 2E8 cells per cm3&lt;br/&gt;Deep Ice (2.5 km deep in Greenland ice sheet): 1E5-1E4 cells per cm3&lt;br/&gt;Instrument detection limit: 1E2 cells per cm3&lt;br/&gt;Medically sterile: 0.1 cells per cm3
    </content>
    <updated>2025-04-26T13:29:30Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqs28ndv9pgv0a8t0fkqtl7fmv97pef4nfespzp4s7tp4u9r8dnwqggzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x6xk6rt</id>
    
      <title type="html">&amp;#34;Habitability&amp;#34; is one of the most misused words in ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqs28ndv9pgv0a8t0fkqtl7fmv97pef4nfespzp4s7tp4u9r8dnwqggzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x6xk6rt" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqszmrvh8sx25a7gj8ytdppn372d9kj7rgrpmmq53lvcxyyecqpfz2cyesrd4&#39;&gt;nevent1q…srd4&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;&amp;#34;Habitability&amp;#34; is one of the most misused words in astrobiology. It is a usually a blurry concept used to justify a mission: “The [insert mission name here] will investigate the habitability of [insert world name here]”.&lt;br/&gt;&lt;br/&gt;More recently, habitability is becoming an actual quantitative and comparative concept. Specifically, how many microbes can exist in an environment?&lt;br/&gt;&lt;br/&gt;Here is an open-access article on Planetary Habitability:&lt;br/&gt;Mendez et al, Astrobiology 2021: &lt;a href=&#34;https://www.liebertpub.com/doi/10.1089/ast.2020.2342&#34;&gt;https://www.liebertpub.com/doi/10.1089/ast.2020.2342&lt;/a&gt;
    </content>
    <updated>2025-04-26T13:27:17Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqszmrvh8sx25a7gj8ytdppn372d9kj7rgrpmmq53lvcxyyecqpfz2czyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xjdjqmu</id>
    
      <title type="html">#astrobiology thread time! A paper came out a few weeks ago about ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqszmrvh8sx25a7gj8ytdppn372d9kj7rgrpmmq53lvcxyyecqpfz2czyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xjdjqmu" />
    <content type="html">
      #astrobiology thread time!&lt;br/&gt;&lt;br/&gt;A paper came out a few weeks ago about &amp;#34;habitability&amp;#34;. Specifically, the habitability of Saturn&amp;#39;s moon Titan. &lt;br/&gt;&lt;br/&gt;We (am one of the co-authors) found that Titan&amp;#39;s chemistry could support the equivalent biomass of a small dog.&lt;br/&gt;&lt;br/&gt;Is that....bad?&lt;br/&gt;(And what does &amp;#34;habitability&amp;#34; mean anyway?)&lt;br/&gt;&lt;br/&gt;Here is the press release from the University of Arizona: &lt;a href=&#34;https://news.arizona.edu/news/saturns-moon-titan-could-harbor-life-only-tiny-amount-study-finds&#34;&gt;https://news.arizona.edu/news/saturns-moon-titan-could-harbor-life-only-tiny-amount-study-finds&lt;/a&gt;&lt;br/&gt;&lt;br/&gt;(Next post will have link to full paper)
    </content>
    <updated>2025-04-26T13:06:14Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsy5xzzy2jmjfe0uyvrvmep7l7lwjy6jc2ktgp4lanpu3605drzspgzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xaxxexs</id>
    
      <title type="html">A symmetrical scene on a #SilentSunday on the shore of the Salish ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsy5xzzy2jmjfe0uyvrvmep7l7lwjy6jc2ktgp4lanpu3605drzspgzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xaxxexs" />
    <content type="html">
      A symmetrical scene on a #SilentSunday on the shore of the Salish Sea.&lt;br/&gt;&lt;br/&gt;Mukilteo, Snohomish County, Washington State&lt;br/&gt; &lt;img src=&#34;https://cdn.masto.host/deepspacesocial/media_attachments/files/114/294/456/653/097/449/original/a46cb6321486abff.jpg&#34;&gt; &lt;br/&gt;
    </content>
    <updated>2025-04-07T03:09:18Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsfprg2flfcned2hddmqnnfaanay0tc5wvnryz5ydxz5lmkmug4a4qzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xfttd2n</id>
    
      <title type="html">As the Huygens probe descended, it took lots of pictures on its ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsfprg2flfcned2hddmqnnfaanay0tc5wvnryz5ydxz5lmkmug4a4qzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xfttd2n" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqs2ffl4vmpw830q8eh7dy7qqewy0zg6wxnjf59weuvt3t46jvdrlxcksn2pq&#39;&gt;nevent1q…n2pq&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;As the Huygens probe descended, it took lots of pictures on its way down to the surface. Those are just a gold mine of information.&lt;br/&gt;&lt;br/&gt;Here is a really fun movie that we call the &amp;#34;bells and whistles&amp;#34; version. It is incredibly information rich. I love watching this over and over. You can see little cartoons showing probe orientation spin, telemetry data, instrument sequences, and images. I love to marvel at the planning that made this happen.&lt;br/&gt;&lt;br/&gt;&lt;a href=&#34;https://science.nasa.gov/resource/titan-descent-data-movie-with-bells-and-whistles/&#34;&gt;https://science.nasa.gov/resource/titan-descent-data-movie-with-bells-and-whistles/&lt;/a&gt;
    </content>
    <updated>2025-01-15T13:52:32Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqs2ffl4vmpw830q8eh7dy7qqewy0zg6wxnjf59weuvt3t46jvdrlxczyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xzl74hv</id>
    
      <title type="html">Ahhhhh. That&amp;#39;s still a mystery! You will read in Wikpedia or ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqs2ffl4vmpw830q8eh7dy7qqewy0zg6wxnjf59weuvt3t46jvdrlxczyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xzl74hv" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqszs4hrqhwsdt90zk88vg24dyl3yes4qhwr4fsq7t0jwkc3gun0masy6k63z&#39;&gt;nevent1q…k63z&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;Ahhhhh. That&amp;#39;s still a mystery! You will read in Wikpedia or some of the literature that it is water ice. &lt;br/&gt;&lt;br/&gt;But actually, we don&amp;#39;t know. It could be ice, or other things: frozen benzene, solid HCN, mixed solid organics. We do not have detailed spectra or other chemical analysis of those rocks vs the sands.&lt;br/&gt;&lt;br/&gt;(Personally, I think it&amp;#39;s probably ice, but I want better proof.)&lt;br/&gt;&lt;br/&gt;(The dark sands I&amp;#39;d lean my guess towards probably organics.)&lt;br/&gt;&lt;br/&gt;It is good to have mysteries! Fun! Explore!
    </content>
    <updated>2025-01-15T13:45:34Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqszs4hrqhwsdt90zk88vg24dyl3yes4qhwr4fsq7t0jwkc3gun0maszyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xmhjrzk</id>
    
      <title type="html">So. Streams or floods, rocks eroding, sorting. Faster than ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqszs4hrqhwsdt90zk88vg24dyl3yes4qhwr4fsq7t0jwkc3gun0maszyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xmhjrzk" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqsru5xzph7lc2l5d65x8ra7c6fell7tuewpeazzltcfafrhe8yd8kq8fjrp9&#39;&gt;nevent1q…jrp9&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;So. Streams or floods, rocks eroding, sorting. Faster than getting covered by atmospheric organic molecules. Got it.&lt;br/&gt;&lt;br/&gt;But what are those rounded rocks made of?
    </content>
    <updated>2025-01-15T13:44:26Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsru5xzph7lc2l5d65x8ra7c6fell7tuewpeazzltcfafrhe8yd8kqzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xwt9rqh</id>
    
      <title type="html">And also what you DON&amp;#39;T SEE. We don&amp;#39;t see a uniform ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsru5xzph7lc2l5d65x8ra7c6fell7tuewpeazzltcfafrhe8yd8kqzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xwt9rqh" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqs95qt5ft0cwmxgeck3tpmzlmqpckvzmddq6vjn37nynpttcr4z78ssynsjv&#39;&gt;nevent1q…nsjv&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;And also what you DON&amp;#39;T SEE. We don&amp;#39;t see a uniform snowscape blanket of organic molecules everywhere. &lt;br/&gt;&lt;br/&gt;That tells us that whatever geological processes happen are faster than covering by organic molecule fallout. &lt;br/&gt;&lt;br/&gt;That fallout happens at a rate of about same as dust builds up in your house if you have a clothes dryer in your house. Max 100 m per Gyr: 0.1 m per Myr, 0.1 mm per kyr or 0.1 microns per year. Give or take an order of magnitude.&lt;br/&gt;&lt;br/&gt;So geology happens on Titan. It&amp;#39;s not boring.
    </content>
    <updated>2025-01-15T13:39:27Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqs95qt5ft0cwmxgeck3tpmzlmqpckvzmddq6vjn37nynpttcr4z78szyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xz95wa6</id>
    
      <title type="html">Just from this surface image, you can figure stuff out. All those ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqs95qt5ft0cwmxgeck3tpmzlmqpckvzmddq6vjn37nynpttcr4z78szyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xz95wa6" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqs93x68vjzfzjesw5fn62992mhwyj7waxtuamvxkcl77xanz2eun6g7krmd0&#39;&gt;nevent1q…rmd0&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;Just from this surface image, you can figure stuff out. All those rocks (whatever they are made of - that is still a mystery), are all rounded, and the same size.&lt;br/&gt;&lt;br/&gt;Rounding suggests erosion, those &amp;#34;rocks&amp;#34; banged together repeatedly. Likes rocks in a river or shore (hint-hint-hint).&lt;br/&gt;&lt;br/&gt;And sorting by some type of process where bigger rocks dropped out somewhere else, and smaller rocks or pieces dropped somewhere else. &lt;br/&gt;&lt;br/&gt;Either a flood deposit or a stream deposit.
    </content>
    <updated>2025-01-15T13:34:40Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqs93x68vjzfzjesw5fn62992mhwyj7waxtuamvxkcl77xanz2eun6gzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x9f32k6</id>
    
      <title type="html">On January 14, 2005 just over 20 years ago today, the Huygens ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqs93x68vjzfzjesw5fn62992mhwyj7waxtuamvxkcl77xanz2eun6gzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x9f32k6" />
    <content type="html">
      On January 14, 2005 just over 20 years ago today, the Huygens probe touched down on the organic-rich surface of Saturn&amp;#39;s moon Titan.&lt;br/&gt;&lt;br/&gt;Here is the scene from Titan&amp;#39;s surface. &lt;a href=&#34;https://photojournal.jpl.nasa.gov/catalog/PIA07232&#34;&gt;https://photojournal.jpl.nasa.gov/catalog/PIA07232&lt;/a&gt;&lt;br/&gt;&lt;br/&gt;Scientists (I&amp;#39;m one of those) have been analyzing this image and the other descent images from the probe for 2 decades. What have we learned from the probe images about the surface of enigmatic moon?&lt;br/&gt;&lt;br/&gt;[Thread]&lt;br/&gt; &lt;img src=&#34;https://cdn.masto.host/deepspacesocial/media_attachments/files/113/832/593/596/621/056/original/e8f4b92179664f02.jpg&#34;&gt; &lt;br/&gt;
    </content>
    <updated>2025-01-15T13:28:26Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqs84qyw86kylnx5u44fwjsq3pw6sydy2jc7tgxc6pml9kgck2skw2gzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xx9uf4k</id>
    
      <title type="html">For example, if someone found a single-dose cure for ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqs84qyw86kylnx5u44fwjsq3pw6sydy2jc7tgxc6pml9kgck2skw2gzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xx9uf4k" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqs2q2cplmtk2hluk8z2qpxs4mez7fpsfs0qhf609crzd8nujey3e7gjnfwvt&#39;&gt;nevent1q…fwvt&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;For example, if someone found a single-dose cure for Alzheimer&amp;#39;s they could probably name their price.&lt;br/&gt;&lt;br/&gt;Market would easily support $100k per person in my guesstimation.&lt;br/&gt;&lt;br/&gt;In US, there are 500,000 new cases of AD per year. So that is a whopping $50B potential market.&lt;br/&gt;&lt;br/&gt;I can&amp;#39;t see the public sector allocating that much even if it was only just to break even economically.&lt;br/&gt;&lt;br/&gt;(Current public funding only about 10% of that and doesn&amp;#39;t have that goal.)
    </content>
    <updated>2025-01-05T21:41:24Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqs2q2cplmtk2hluk8z2qpxs4mez7fpsfs0qhf609crzd8nujey3e7gzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xgc4zas</id>
    
      <title type="html">Would agree sorta. Some of these issues are baked into the ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqs2q2cplmtk2hluk8z2qpxs4mez7fpsfs0qhf609crzd8nujey3e7gzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xgc4zas" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqsyupqvqu6u7q527wf4ty9pckwjtc7f92jden9fcfdygyrjgzt3yug2dm35c&#39;&gt;nevent1q…m35c&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;Would agree sorta. Some of these issues are baked into the system.&lt;br/&gt;&lt;br/&gt;However, antibiotics, antifungals, and antiparasitics do produce cures. Nobody would buy a bacterial-stat when a bacterial-cide was available.&lt;br/&gt;&lt;br/&gt;Same with other drugs. All things equal, a cure for cancer or Alzheimer&amp;#39;s or whatever would always outcompete a long-term treatment for same disease.&lt;br/&gt;&lt;br/&gt;In this case the competitiveness works for you to incentivise better treatments.
    </content>
    <updated>2025-01-05T21:27:29Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsdr6l86u0suh3f74t8cktjjvh4xpyr48yw86ann8nqyhdeml23ylqzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x5nvd3t</id>
    
      <title type="html">Costs for clinical trials should be the same for either private ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsdr6l86u0suh3f74t8cktjjvh4xpyr48yw86ann8nqyhdeml23ylqzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x5nvd3t" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqs0dfmjzdqxhc7vk22fxfemrrnup50d6rkn4at7geytx0gdxj4nacgjjgjjw&#39;&gt;nevent1q…gjjw&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;Costs for clinical trials should be the same for either private or public sector.&lt;br/&gt;&lt;br/&gt;I honestly don&amp;#39;t know what drives clinical costs. I&amp;#39;ve always assumed it is the personnell costs of record-keeping, administration developing protocols, dealing with Investigational Revew Boards, etc.&lt;br/&gt;&lt;br/&gt;(I also dont have a good handle on R&amp;amp;D costs spent vs. drugs approved for public sector efforts. Any ideas?)
    </content>
    <updated>2025-01-05T19:56:32Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqs2h3u3jsanvh9fg202qfrdnh5gpzmqctnm3nwzd9y5wd7x5c8vqgczyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xa394uy</id>
    
      <title type="html">Sorry. I wasnt super-clear in explanation. Was assuming a total ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqs2h3u3jsanvh9fg202qfrdnh5gpzmqctnm3nwzd9y5wd7x5c8vqgczyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xa394uy" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqs8lzvguyg0up5rfnuvznv4l3aqgdkps2077lyp9u9yxyum2cr5qect4jefe&#39;&gt;nevent1q…jefe&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;Sorry. I wasnt super-clear in explanation.&lt;br/&gt;&lt;br/&gt;Was assuming a total market potential of $1B per year, but assumed the successful drug would only capture 50% of that market averaged over 16 years.&lt;br/&gt;&lt;br/&gt;So $500M per year actual sales over 16 years gives $8B total which is just enough to cover costs. No profit.&lt;br/&gt;&lt;br/&gt;Means you need $1B per year potential to even think about a program.&lt;br/&gt;&lt;br/&gt;(Which, as you stated, economocally limits targets.)
    </content>
    <updated>2025-01-05T19:49:26Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsgsarhrkxqfkm9uu248cnydmu0lgxlkg77hmkf2eysn3ycfk4u0lszyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xh0473q</id>
    
      <title type="html">...the other implication is that you gotta make up for that ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsgsarhrkxqfkm9uu248cnydmu0lgxlkg77hmkf2eysn3ycfk4u0lszyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xh0473q" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqsx3szmlqxjzqplmfa8ndv7nh23069zth6xynlmhcj72gvujfs3j4gafl556&#39;&gt;nevent1q…l556&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;...the other implication is that you gotta make up for that initial cash outlay on the back end.&lt;br/&gt;&lt;br/&gt;So assume 16 years of exclusive patent period and average during that period of 50% market penetration you need to have a $1B per year drug to make up for your initial costs.&lt;br/&gt;&lt;br/&gt;Big question: Is there a $1B per year driving need RIGHT NOW for a new antibiotic?&lt;br/&gt;&lt;br/&gt;(Remember, there are other generic antibiotics, insurance companies will want to try those first.)
    </content>
    <updated>2025-01-05T17:31:42Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsx3szmlqxjzqplmfa8ndv7nh23069zth6xynlmhcj72gvujfs3j4gzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xhwth6z</id>
    
      <title type="html">So, if you want new antibiotics, someone&amp;#39;s gotta: 1) pony up ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsx3szmlqxjzqplmfa8ndv7nh23069zth6xynlmhcj72gvujfs3j4gzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xhwth6z" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqsqhxf8avhnqm893tufaxg0f2n9pvcpwl8gl6nk08u9fqxxc3xddcqs874c6&#39;&gt;nevent1q…74c6&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;So, if you want new antibiotics, someone&amp;#39;s gotta:&lt;br/&gt;&lt;br/&gt;1) pony up a several BILLION dollars of dedicated R&amp;amp;D effort for just this.&lt;br/&gt;&lt;br/&gt;2) find some way to improve that 96% failure rate.&lt;br/&gt;&lt;br/&gt;That 96% is ingrained in every pharma scientists brain. Keeps us humble. There is always a &amp;#34;bold new paradigm to accelerate drug discovery&amp;#34; that never moves the needle.
    </content>
    <updated>2025-01-05T17:27:33Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsqhxf8avhnqm893tufaxg0f2n9pvcpwl8gl6nk08u9fqxxc3xddcqzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xxzm7xp</id>
    
      <title type="html">(those are very old numbers, btw. Prolly double now.) At each ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsqhxf8avhnqm893tufaxg0f2n9pvcpwl8gl6nk08u9fqxxc3xddcqzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xxzm7xp" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqswyxqfyl3refwhxxwuaprmfaq03vqzeul3suahdu07xasc33rq9cq2a3e2t&#39;&gt;nevent1q…3e2t&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;(those are very old numbers, btw. Prolly double now.)&lt;br/&gt;&lt;br/&gt;At each step, about 50% attrition.&lt;br/&gt;(This is why press releases finding something active #InMice is so silly.)&lt;br/&gt;&lt;br/&gt;So it COSTS $620 million to find a new drug if everything works.&lt;br/&gt;&lt;br/&gt;How much do pharma companies actually SPEND to find a new drug?&lt;br/&gt;(So include failure costs)&lt;br/&gt;&lt;br/&gt;Turns out about $8B per drug.&lt;br/&gt;(Reported R&amp;amp;D costs per new drug approval)
    </content>
    <updated>2025-01-05T17:22:23Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqswyxqfyl3refwhxxwuaprmfaq03vqzeul3suahdu07xasc33rq9cqzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x7xfg0n</id>
    
      <title type="html">Former medicinal chemist here. Developing drugs is really hard. ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqswyxqfyl3refwhxxwuaprmfaq03vqzeul3suahdu07xasc33rq9cqzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x7xfg0n" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqsr2neu26y52qm0w3rf7aqvt3epn2jw4qcrumfctkscq4sydvxk0dqmcvugc&#39;&gt;nevent1q…vugc&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;Former medicinal chemist here.&lt;br/&gt;&lt;br/&gt;Developing drugs is really hard. We have a 96% failure rate. &lt;br/&gt;&lt;br/&gt;Here is some math.&lt;br/&gt;Assume $300K FTE rate per scientist.&lt;br/&gt;&lt;br/&gt;Find a preclinical candidate: $15M&lt;br/&gt;Tox testing: $5M&lt;br/&gt;&lt;br/&gt;Phase 1 clinical trials (safety in healthy subjects - is it safe?): $50M&lt;br/&gt;&lt;br/&gt;Phase 2 clinical trails (efficacy in diseased subjects - does it work?): $250M&lt;br/&gt;&lt;br/&gt;Phase 3 clinical trials (liability): $300M&lt;br/&gt;&lt;br/&gt;Total: $620M if everything works.&lt;br/&gt;&lt;br/&gt;But, 96% failure rate.
    </content>
    <updated>2025-01-05T17:16:38Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqstvngz0c4w2azdr63lac6j9f266w2hztxdcysn9tjp33l5l77yjcqzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x5auyr5</id>
    
      <title type="html">haha! Perfect timing! I just switched my field compass&amp;#39; ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqstvngz0c4w2azdr63lac6j9f266w2hztxdcysn9tjp33l5l77yjcqzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x5auyr5" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqs0hxusyrea7kp8k4uvaesfq8tnxk7y9qh2qwgqggujm9wes9tkxeglum9d8&#39;&gt;nevent1q…m9d8&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;haha! Perfect timing! I just switched my field compass&amp;#39; declination offset just yesterday!&lt;br/&gt;&lt;br/&gt;Here is a handy calculator from NOAA where you can enter the target lat lon (for a future field expedition) and get the declination offset:&lt;br/&gt;&lt;a href=&#34;https://www.ngdc.noaa.gov/geomag/calculators/mobileDeclination.shtml#WMM&#34;&gt;https://www.ngdc.noaa.gov/geomag/calculators/mobileDeclination.shtml#WMM&lt;/a&gt;
    </content>
    <updated>2024-12-23T00:51:54Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsfvn5wunn75a0rh64jsw52s52wnan5fest45lzy5mq9dp4azafg0qzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xg8mz5y</id>
    
      <title type="html">Picnic Point County Park, Snohomish County, Washington. ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsfvn5wunn75a0rh64jsw52s52wnan5fest45lzy5mq9dp4azafg0qzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xg8mz5y" />
    <content type="html">
      Picnic Point County Park, Snohomish County, Washington.&lt;br/&gt;&lt;br/&gt;#SalishSea&lt;br/&gt;&lt;br/&gt;#SilentSundays&lt;br/&gt; &lt;img src=&#34;https://cdn.masto.host/deepspacesocial/media_attachments/files/113/619/882/609/347/835/original/9254c54d994dbd89.jpg&#34;&gt; &lt;br/&gt;
    </content>
    <updated>2024-12-08T23:53:33Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqs2ptd464qeklvyf9enrwm7tcvgxs62vrqpujmfwc7se7a7uve0swqzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xffsykt</id>
    
      <title type="html">#SilentSunday Orange County, North Carolina. ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqs2ptd464qeklvyf9enrwm7tcvgxs62vrqpujmfwc7se7a7uve0swqzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xffsykt" />
    <content type="html">
      #SilentSunday&lt;br/&gt;&lt;br/&gt;Orange County, North Carolina.&lt;br/&gt; &lt;img src=&#34;https://cdn.masto.host/deepspacesocial/media_attachments/files/113/341/361/215/397/732/original/9f4db8c29e9b9841.jpg&#34;&gt; &lt;br/&gt;
    </content>
    <updated>2024-10-20T19:20:51Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsfjk0fmyevj988xw5c7ds0dentwdxph9ehggy5902shjfty97l6tszyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xv83edc</id>
    
      <title type="html">All these ideas are described in: Waite et al (2024) ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsfjk0fmyevj988xw5c7ds0dentwdxph9ehggy5902shjfty97l6tszyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xv83edc" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqs9yxpcgexaxkp5nfre5xhs7lqsqf6d44g0hw2x7au3geund8emx4stwjaqv&#39;&gt;nevent1q…jaqv&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;All these ideas are described in: Waite et al (2024) &amp;#34;MASPEX-Europa: The Europa Clipper Neutral Gas Mass Specteometer Investigation.&amp;#34; Space Science Reviews 220:30.&lt;br/&gt;&lt;br/&gt;Open access (free!!!!) here: &lt;a href=&#34;https://link.springer.com/article/10.1007/s11214-024-01061-6&#34;&gt;https://link.springer.com/article/10.1007/s11214-024-01061-6&lt;/a&gt;&lt;br/&gt;(Heads up its 126 pages long.)&lt;br/&gt;&lt;br/&gt;Specifically, ceck out Europa MASPRX Science Objective 3: &amp;#34;Search for potential biosignatures in the Europs enviroment.&amp;#34;&lt;br/&gt;&lt;br/&gt;Good hunting!
    </content>
    <updated>2024-10-15T02:04:29Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqs9yxpcgexaxkp5nfre5xhs7lqsqf6d44g0hw2x7au3geund8emx4szyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x5vmwzg</id>
    
      <title type="html">Some fatty acids (lawyer warning here: &amp;#34;this only applies to ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqs9yxpcgexaxkp5nfre5xhs7lqsqf6d44g0hw2x7au3geund8emx4szyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x5vmwzg" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqsx55fyrcne755633p0qdatxulvsd8ul0g30j0fcv5kxvlwy508l3q577ycw&#39;&gt;nevent1q…7ycw&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;Some fatty acids (lawyer warning here: &amp;#34;this only applies to satutated linear (unbranched) fatty acids in certain life forms on Earth.&amp;#34;) have a 2C homologation pattern because of how they were built up by enzymes. (Fatty Acid Synthesis - FAS pathway. Although there is another pathway at high pressures.)&lt;br/&gt;&lt;br/&gt;That might give a pattern in.the MS that could be considered a biosignature - a hint of something exciting.
    </content>
    <updated>2024-10-15T02:01:50Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsx55fyrcne755633p0qdatxulvsd8ul0g30j0fcv5kxvlwy508l3qzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x42ss26</id>
    
      <title type="html">Other clues are that a few different pieces get assembled up into ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsx55fyrcne755633p0qdatxulvsd8ul0g30j0fcv5kxvlwy508l3qzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x42ss26" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqsyrp6m5fh3nrfrqj947wkw7jdj60lp2c6ll6mvq68zj7l7c85yw4gzjyy9k&#39;&gt;nevent1q…yy9k&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;Other clues are that a few different pieces get assembled up into bigger things. When amino acids get assembled up they become proteins and enzymes. Assembled up, nucleotide bases become DNA and RNA.&lt;br/&gt;&lt;br/&gt;Some small structures (CH2CH2) and isoprenyl get built up into membrane molecules. (I like membrane molecules.)&lt;br/&gt;&lt;br/&gt;When you smack them with an MS. You see these repeating breakdown  chunks as the links sometimes fall apart because the links and connectors are weaker.
    </content>
    <updated>2024-10-15T01:55:39Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsyrp6m5fh3nrfrqj947wkw7jdj60lp2c6ll6mvq68zj7l7c85yw4gzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xysc4xy</id>
    
      <title type="html">One clue, is that there are many many possible structural isomers ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsyrp6m5fh3nrfrqj947wkw7jdj60lp2c6ll6mvq68zj7l7c85yw4gzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xysc4xy" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqstkg47nxexqd3xqn08e0t2zrrvuauqx9k52hukj79n93zyrxfm80qk6va4e&#39;&gt;nevent1q…va4e&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;One clue, is that there are many many possible structural isomers for a molecule of a given size. Abiotic chemistry makes a (sorta) random mess.&lt;br/&gt;&lt;br/&gt;In contrast, biology uses molecular things. So you might see a few key molecules, but lots of them. Lower diversity.&lt;br/&gt;&lt;br/&gt;As an example, go into a forest after a windstorm, wood of all sorts of lengths lying everywhere. But go into a lumberyard, and sizes and  lengths are pretty standard: 8ft, and 12 ft.&lt;br/&gt;&lt;br/&gt;Standardized stuff makes building things easier.
    </content>
    <updated>2024-10-15T01:50:58Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqstkg47nxexqd3xqn08e0t2zrrvuauqx9k52hukj79n93zyrxfm80qzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x2255us</id>
    
      <title type="html">Europa Clipper is a mission to chatacterize the ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqstkg47nxexqd3xqn08e0t2zrrvuauqx9k52hukj79n93zyrxfm80qzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x2255us" />
    <content type="html">
      Europa Clipper is a mission to chatacterize the &amp;#34;habitability&amp;#34; of Europa. That is its goal. The team has been very very careful to not claim that it is looking for life. It is effectively being pitched as an early precursor #OceanWorld #astrobiology mission.&lt;br/&gt;&lt;br/&gt;But...if life were there and evidence was detected by the spacecraft, what instruments might give the hint of a biosignature?&lt;br/&gt;&lt;br/&gt;That might be the mass spectrometer MASPEX.&lt;br/&gt;&lt;br/&gt;What could it detect?
    </content>
    <updated>2024-10-15T01:44:24Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsylxnpxcdgh5tjn3pydg2r2ydyy4qeqhf56zdu2fhjvnngk5lypqqzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x57cvqc</id>
    
      <title type="html">Europa Clipper unfolded its solar panels! ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsylxnpxcdgh5tjn3pydg2r2ydyy4qeqhf56zdu2fhjvnngk5lypqqzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x57cvqc" />
    <content type="html">
      Europa Clipper unfolded its solar panels!&lt;br/&gt;&lt;br/&gt;&lt;a href=&#34;https://blogs.nasa.gov/europaclipper/2024/10/14/solar-arrays-on-nasas-europa-clipper-fully-deployed-in-space/&#34;&gt;https://blogs.nasa.gov/europaclipper/2024/10/14/solar-arrays-on-nasas-europa-clipper-fully-deployed-in-space/&lt;/a&gt;
    </content>
    <updated>2024-10-14T20:16:40Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsp70j7td3026gqztfn9fvf63e86vcdzp0lgv6hkff74mfer3r4zqczyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xdhpz66</id>
    
      <title type="html">Europa Clipper launch live stream: ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsp70j7td3026gqztfn9fvf63e86vcdzp0lgv6hkff74mfer3r4zqczyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xdhpz66" />
    <content type="html">
      Europa Clipper launch live stream:&lt;br/&gt;&lt;a href=&#34;https://www.youtube.com/live/lQToTWKwtuw?si=hIJiB7ZE7j5hxFTE&#34;&gt;https://www.youtube.com/live/lQToTWKwtuw?si=hIJiB7ZE7j5hxFTE&lt;/a&gt;&lt;br/&gt;&lt;br/&gt;Launch at 12:06 EDT. Less than 1 h!&lt;br/&gt;&lt;br/&gt;Everything looks good now!
    </content>
    <updated>2024-10-14T15:08:35Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsyleqtweylqjpnthyugx6tfzkl3fy2lqadpwulp050ef3aqlew0egzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x6js7ke</id>
    
      <title type="html">(Read last sentence in &amp;#39;Shigella-classification&amp;#39; section ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsyleqtweylqjpnthyugx6tfzkl3fy2lqadpwulp050ef3aqlew0egzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x6js7ke" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqs27ufle9tkatce99ey5agrwjarcjzlptxcr7vudggdwu4ug37rakqdfh2yr&#39;&gt;nevent1q…h2yr&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;(Read last sentence in &amp;#39;Shigella-classification&amp;#39; section in the Wikipedia entry)&lt;br/&gt;&lt;br/&gt;&lt;a href=&#34;https://en.m.wikipedia.org/wiki/Shigella&#34;&gt;https://en.m.wikipedia.org/wiki/Shigella&lt;/a&gt;
    </content>
    <updated>2024-10-05T20:57:01Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqs27ufle9tkatce99ey5agrwjarcjzlptxcr7vudggdwu4ug37rakqzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x6fn3l7</id>
    
      <title type="html">Also &amp;#34;taxon in disguise&amp;#34; where they figure out later that ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqs27ufle9tkatce99ey5agrwjarcjzlptxcr7vudggdwu4ug37rakqzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x6fn3l7" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqsgex9g6sx3lz3m8xyg6hkmkly4a5ucerpf9kpyzj3r70ekgd8jklcxx4z8q&#39;&gt;nevent1q…4z8q&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;Also &amp;#34;taxon in disguise&amp;#34; where they figure out later that things fit together differently.&lt;br/&gt;&lt;br/&gt;A great example is genus Shigella (one species causes dysentery. Very bad.). Turns out...the whole genus is (are?) just strains of E coli. So it should be be reclassified.&lt;br/&gt;&lt;br/&gt;But there is so much negative publicity (the dysentery thing), that it would be dangerously confusing to reclassify it.&lt;br/&gt;&lt;br/&gt;So it remains as a neat factoid for those &amp;#34;in the know.&amp;#34;
    </content>
    <updated>2024-10-05T20:54:18Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqs22h0ev4jffr4pr03watr34zudr09uvrznq6yx00nrykhdrp98wtgzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xdnfcq2</id>
    
      <title type="html">Geological Society of America pre-conference field trip thread! ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqs22h0ev4jffr4pr03watr34zudr09uvrznq6yx00nrykhdrp98wtgzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xdnfcq2" />
    <content type="html">
      Geological Society of America pre-conference field trip thread!&lt;br/&gt;&lt;br/&gt;Ever wonder what a GSA preconference #geology field trip is like? Want to see some of the geological wonders of  Southern California?&lt;br/&gt;&lt;br/&gt;As one of the optional field trips for #GSAConnects2024, our trip went to Anza Borrego/Salton Sea area and was designed to highlight key geoscience educational areas along the way. &lt;br/&gt;&lt;br/&gt;The goal was to share techniques for teaching and explaining geoscience concepts to students and the public.&lt;br/&gt;&lt;br/&gt;[1/15]&lt;br/&gt; &lt;img src=&#34;https://cdn.masto.host/deepspacesocial/media_attachments/files/113/217/556/635/778/181/original/62e464f9100bc4ff.jpg&#34;&gt; &lt;br/&gt;
    </content>
    <updated>2024-09-28T22:37:48Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqs99fxnynmm2rkkxc7qupe7ljeg0836hydxelmma6uwpmz8a0rnxrczyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xlyazar</id>
    
      <title type="html">Ever wonder if there are analogs for Saturn&amp;#39;s moon Titan in ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqs99fxnynmm2rkkxc7qupe7ljeg0836hydxelmma6uwpmz8a0rnxrczyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xlyazar" />
    <content type="html">
      Ever wonder if there are analogs for Saturn&amp;#39;s moon Titan in Death Valley? Would you like to try a clickable map choose-your-own-adventure-style StoryMap?&lt;br/&gt;&lt;br/&gt;I got you. Right here:&lt;br/&gt;&lt;br/&gt;&lt;a href=&#34;https://uploads.knightlab.com/storymapjs/309aee613c9ca5466ff4084b009c1549/analogs-of-saturn-s-moon-titan-in-death-valley-national-park-draft0/index.html&#34;&gt;https://uploads.knightlab.com/storymapjs/309aee613c9ca5466ff4084b009c1549/analogs-of-saturn-s-moon-titan-in-death-valley-national-park-draft0/index.html&lt;/a&gt;
    </content>
    <updated>2024-09-01T02:19:00Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqs2pvderr98tmv7cxvkryy23ya3ydul4y9fj4pdhqydmkxq6ha03qgzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x3zw4ha</id>
    
      <title type="html">Heya #mapstodon , Has anyone used StoryMap JS? Reccomend? Any ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqs2pvderr98tmv7cxvkryy23ya3ydul4y9fj4pdhqydmkxq6ha03qgzyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x3zw4ha" />
    <content type="html">
      Heya #mapstodon ,&lt;br/&gt;&lt;br/&gt;Has anyone used StoryMap JS?&lt;br/&gt;&lt;br/&gt;Reccomend? Any good tutorials or tips?
    </content>
    <updated>2024-08-31T15:24:11Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsq5y5efdwujv2736seu2mjw8ajp95qndvwnpsva6d94rvfqvsckgszyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x7qdp0u</id>
    
      <title type="html">I just captured a one-in-a-million image. In the woods just off ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsq5y5efdwujv2736seu2mjw8ajp95qndvwnpsva6d94rvfqvsckgszyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573x7qdp0u" />
    <content type="html">
      I just captured a one-in-a-million image.&lt;br/&gt;In the woods just off our front deck.&lt;br/&gt;&lt;br/&gt;I think it wants me to go with it to Narnia.&lt;br/&gt; &lt;img src=&#34;https://cdn.masto.host/deepspacesocial/media_attachments/files/112/962/755/219/091/509/original/a632d06d2220117e.jpg&#34;&gt; &lt;br/&gt;
    </content>
    <updated>2024-08-14T22:35:41Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsy30xj2pqxjl88lm4u446n6y8attuxnaytuuc0ln8nvh7anjyze9czyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xkzj2f9</id>
    
      <title type="html">No complex life without oxygen? &amp;lt;Loricifera has entered the ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsy30xj2pqxjl88lm4u446n6y8attuxnaytuuc0ln8nvh7anjyze9czyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xkzj2f9" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqsxwpnsnuww4nvlz8rh7yegx58f5nx84hg35snxfdgnvjwyjm0vpwqar289a&#39;&gt;nevent1q…289a&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;No complex life without oxygen?&lt;br/&gt;&lt;br/&gt;&amp;lt;Loricifera has entered the chat&amp;gt;&lt;br/&gt;&lt;br/&gt;&lt;a href=&#34;https://en.wikipedia.org/wiki/Loricifera&#34;&gt;https://en.wikipedia.org/wiki/Loricifera&lt;/a&gt;
    </content>
    <updated>2024-08-12T15:45:36Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsdypq8jy7hwvadz57jjmgh68thttelu7c978wc5vvm0xqzc3yghsczyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xstm4e3</id>
    
      <title type="html">Blackwood Farm Park, Chapel Hill, North Carolina. #SilentSunday ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsdypq8jy7hwvadz57jjmgh68thttelu7c978wc5vvm0xqzc3yghsczyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xstm4e3" />
    <content type="html">
      Blackwood Farm Park, Chapel Hill, North Carolina.&lt;br/&gt;&lt;br/&gt;#SilentSunday&lt;br/&gt; &lt;img src=&#34;https://cdn.masto.host/deepspacesocial/media_attachments/files/112/866/084/630/834/215/original/61da7ec1fcc2d761.jpg&#34;&gt; &lt;br/&gt;
    </content>
    <updated>2024-07-28T20:53:02Z</updated>
  </entry>

  <entry>
    <id>https://yabu.me/nevent1qqsqw30seftxp0h5n3xj37wda7td0m6nds2rcdtg0skpwwxfqdkzeeczyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xsrgw67</id>
    
      <title type="html">I let my lettuce bolt last year. Chopped it in fall before I ...</title>
    
    <link rel="alternate" href="https://yabu.me/nevent1qqsqw30seftxp0h5n3xj37wda7td0m6nds2rcdtg0skpwwxfqdkzeeczyp3lvlr07fyskctya8nr9d4typjy9d8esh9u4fyuwjetaac9k573xsrgw67" />
    <content type="html">
      In reply to &lt;a href=&#39;/nevent1qqsrrxwyvfaahhuje57ke4ew9awzu4pjdggm58lg3y52kxj989y5gjqa0q6va&#39;&gt;nevent1q…q6va&lt;/a&gt;&lt;br/&gt;_________________________&lt;br/&gt;&lt;br/&gt;I let my lettuce bolt last year. Chopped it in fall before I threw into compost tumbler. In early spring, I found volunteer little lettuce-lings at the three-leaf stage  where I had chopped it up. Moved them to a bed and they did just fine. (Pretty sure it was Tropicana lettuce variety, btw.)&lt;br/&gt;&lt;br/&gt;Big lesson: Let stuff bolt in summer/fall. Chop up in different areas just before putting into composr. Look for volunteers in those areas in very early spring.&lt;br/&gt; &lt;img src=&#34;https://cdn.masto.host/deepspacesocial/media_attachments/files/112/626/739/027/141/074/original/ccf7f9b6d7591562.jpg&#34;&gt; &lt;br/&gt;
    </content>
    <updated>2024-06-16T14:27:16Z</updated>
  </entry>

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