no, that is why coracle shows replyguy and nostrudel doesn't currently, if you haven't got replyguy relays on your list (as i do)
i don't think that searching other people's relay lists was the point of NIP-65, rather, it was about decentralization - ie, if client reads from inbox and posts to outbox then other clients can read that user's events from users outbox and post to users inbox
you aren't alone in having this confusion, this assumption is baked into how #coracle looks for posts and why even though i have no primal or damus relays i see replyguy on coracle (and i've stopped using it again because of this)
hodlbod (npub1jlr…ynqn) maybe an idea for how to avoid pulling replyguy events is to only look for events with pubkey of follow user not for tags containing it as well, this eliminates getting replyguy replies when you search a follow's posts on follows relay lists (app and in/outbox both)